adisease

Showing entry for Osteoporosis, Senile

General Disease Information
BXGD Id	BXGD002159
Disease Name	Osteoporosis, Senile
Disease CUI Id	C0029459
MeSH Codes	C18 C05
Disease Class Name	Nutritional and Metabolic Diseases; Musculoskeletal Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O95622	BXGT005386	Adenylate cyclase type 5	111	reviewed
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02675	BXGT005916	Fibrinogen beta chain	2244	reviewed	Signaling
P02788	BXGT005963	Lactotransferrin	4057	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07237	BXGT006576	Protein disulfide-isomerase	5034	reviewed
P07355	BXGT006609	Annexin A2	302	reviewed
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P14618	BXGT008027	Pyruvate kinase PKM	5315	reviewed	Kinase
P18206	BXGT008389	Vinculin	7414	reviewed
P25787	BXGT009069	Proteasome subunit alpha type-2	5683	reviewed
P28066	BXGT009227	Proteasome subunit alpha type-5	5686	reviewed
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P31939	BXGT009584	Bifunctional purine biosynthesis protein PURH	471	reviewed	Enzyme
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P50479	BXGT010804	PDZ and LIM domain protein 4	8572	reviewed	Cellular structure
P55809	BXGT011127	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial	5019	reviewed	Enzyme
P58335	BXGT011233	Anthrax toxin receptor 2	118429	reviewed	Receptor
P60174	BXGT011294	Triosephosphate isomerase	7167	reviewed	Enzyme
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P67936	BXGT011570	Tropomyosin alpha-4 chain	7171	reviewed	Cellular structure
P68363	BXGT011594	Tubulin alpha-1B chain	10376	reviewed	Cellular structure
Q01081	BXGT012566	Splicing factor U2AF 35 kDa subunit	7307	reviewed
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99685	BXGT019948	Monoglyceride lipase	11343	reviewed	Enzyme
Q9HCE7	BXGT020532	E3 ubiquitin-protein ligase SMURF1	57154	reviewed	Enzyme
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
P20809	BXGT025043	Interleukin-11	3589	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}