adisease

Showing entry for Necrosis

General Disease Information
BXGD Id	BXGD001996
Disease Name	Necrosis
Disease CUI Id	C0027540
MeSH Codes	C23
Disease Class Name	Pathological Conditions, Signs and Symptoms
Semantic Type	Organ or Tissue Function
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O95750	BXGT005395	Fibroblast growth factor 19	9965	reviewed	Signaling
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04156	BXGT006156	Major prion protein	5621	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05413	BXGT006355	Fatty acid-binding protein, heart	2170	reviewed
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P20810	BXGT008602	Calpastatin	831	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P45379	BXGT010459	Troponin T, cardiac muscle	7139	reviewed	Cellular structure
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P50440	BXGT010798	Glycine amidinotransferase, mitochondrial	2628	reviewed
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P78540	BXGT011848	Arginase-2, mitochondrial	384	reviewed	Enzyme
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q8NBN7	BXGT018540	Retinol dehydrogenase 13	112724	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q9UHL4	BXGT021703	Dipeptidyl peptidase 2	29952	reviewed	Enzyme
Q9UHX1	BXGT021707	Poly(U)-binding-splicing factor PUF60	22827	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P21731	BXGT026174	Thromboxane A2 receptor	6915	reviewed	G-protein coupled receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}