PharmaCoNets
.
Lomustine
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PharmaCoNets of Lomustine (S
PCN
: 0.14 )
Lomustine regulated-network (S
DN
: 0.64)
Drug Name
Pathway ID
Pathway name
P-value
No. of gene members
UniProt AC
Gene name
Detail of Coexpression
Lomustine
hsa03450
Non-homologous end-joining
1.14E-02
1
Q9NP87
POLM
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q93045
STMN2
Stathmin-2
Q9NP87
POLM
DNA-directed DNA/RNA polymerase mu
-0.739
Lomustine
hsa04010
MAPK signaling pathway
4.93E-02
1
P16949
STMN1
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P16949
STMN1
Stathmin
P16949
STMN1
Stathmin
1
Lomustine
hsa04115
p53 signaling pathway
1.13E-02
2
O15151, Q9Y6P5
MDM4, SESN1
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q93045
STMN2
Stathmin-2
O15151
MDM4
Protein Mdm4
0.708
Q93045
STMN2
Stathmin-2
Q9Y6P5
SESN1
Sestrin-1
0.7
Lomustine
hsa04962
Vasopressin-regulated water reabsorption
3.40E-02
1
Q9UJW0
DCTN4
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q93045
STMN2
Stathmin-2
Q9UJW0
DCTN4
Dynactin subunit 4
0.716
Lomustine
hsa05033
Nicotine addiction
4.50E-02
1
P78334
GABRE
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q93045
STMN2
Stathmin-2
P78334
GABRE
Gamma-aminobutyric acid receptor subunit epsilon
-0.725
Lomustine
hsa05206
MicroRNAs in cancer
3.81E-02
1
P16949
STMN1
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
P16949
STMN1
Stathmin
P16949
STMN1
Stathmin
1
Community members of Lomustine (S
DC
: 0.22)
UniProtAC
Gene Name
Protein Name
Reported/
Predicted
DisGeNET
S
PV
S
drugability
S
HiSBiN
S
DisG
Q93045
STMN2
StathminNone2
Predicted
0
0.2577
0.0042
0
0.1373
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
Q93045
STMN2
0.633
None
None
P16949
STMN1
Stathmin
Predicted
0
0.0905
0.0048
0.2572
0.312
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
P16949
STMN1
0.721
None
None
This pair is Reported in Drugbank.
Gene name
UniProt_ID
Bioactivity
Value (nM)
