PharmaCoNets
.
Flecainide
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PharmaCoNets of Flecainide (S
PCN
: 0.11 )
Flecainide regulated-network (S
DN
: 0.16)
Drug Name
Pathway ID
Pathway name
P-value
No. of gene members
UniProt AC
Gene name
Detail of Coexpression
Flecainide
hsa00340
Histidine metabolism
3.28E-02
1
O95954
FTCD
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q92736
RYR2
Ryanodine receptor 2
O95954
FTCD
Formimidoyltransferase-cyclodeaminase
0.78
Flecainide
hsa00670
One carbon pool by folate
4.88E-02
1
O95954
FTCD
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q92736
RYR2
Ryanodine receptor 2
O95954
FTCD
Formimidoyltransferase-cyclodeaminase
0.78
Flecainide
hsa04360
Axon guidance
2.65E-02
2
P20936, P34925
RASA1, RYK
More
Genes in community(ComG)
Gene name of ComG
Protein name of ComG
Co-expressed genes in pathway (PathG)
Gene name of PathG
Protein name of PathG
Coexpression
Q92736
RYR2
Ryanodine receptor 2
P20936
RASA1
Ras GTPase-activating protein 1
-0.73
Q92736
RYR2
Ryanodine receptor 2
P34925
RYK
Tyrosine-protein kinase RYK
-0.7
Community members of Flecainide (S
DC
: 0.67)
UniProtAC
Gene Name
Protein Name
Reported/
Predicted
DisGeNET
S
PV
S
drugability
S
HiSBiN
S
DisG
Q92736
RYR2
Ryanodine receptor 2
Reported
0
0.3011
0.0221
0.4706
0.6655
BDBM ID
C.S.
Homologus UniProt ID
Gene Name
I.S.
Text mining Similar drug DB ID
C.S.
None
None
None
None
None
None
None
This pair is Reported in Drugbank.
Gene name
UniProt_ID
Bioactivity
Value (nM)
