| Drug Name | Pathway ID | Pathway name | P-value | No. of gene members | UniProt AC | Gene name | Detail of Coexpression | |
|---|
| Colchiceine | hsa00010 | Glycolysis / Gluconeogenesis | 1.18E-02 | 2 | P60174, P06744 | TPI1, GPI | More | | | Colchiceine | hsa00030 | Pentose phosphate pathway | 1.69E-02 | 2 | P60891, P37837 | PRPS1, TALDO1 | More | | | Colchiceine | hsa00052 | Galactose metabolism | 1.03E-02 | 2 | P06280, O43451 | GLA, MGAM | More | | | Colchiceine | hsa00053 | Ascorbate and aldarate metabolism | 1.80E-02 | 2 | P51648, Q9UEF7 | ALDH3A2, KL | More | | | Colchiceine | hsa00220 | Arginine biosynthesis | 3.83E-02 | 2 | P05089, P49448 | ARG1, GLUD2 | More | | | Colchiceine | hsa00310 | Lysine degradation | 4.27E-02 | 2 | Q96KQ7, P51648 | EHMT2, ALDH3A2 | More | | | Colchiceine | hsa00500 | Starch and sucrose metabolism | 1.67E-02 | 2 | O43451, P06737 | MGAM, PYGL | More | | | Colchiceine | hsa00520 | Amino sugar and nucleotide sugar metabolism | 2.11E-02 | 3 | Q16222, Q9Y223, P06865 | UAP1, GNE, HEXA | More | | | Colchiceine | hsa00561 | Glycerolipid metabolism | 4.36E-03 | 3 | O14494, P51648, P23743 | PLPP1, ALDH3A2, DGKA | More | | | Colchiceine | hsa00600 | Sphingolipid metabolism | 4.56E-02 | 3 | Q9BX95, Q06136, P06280 | SGPP1, FVT1, GLA | More | | | Colchiceine | hsa00603 | Glycosphingolipid biosynthesis - globo and isoglobo series | 8.72E-03 | 2 | P06865, O75752 | HEXA, B3GALNT1 | More | | | Colchiceine | hsa00604 | Glycosphingolipid biosynthesis - ganglio series | 2.46E-02 | 2 | P06865, Q9H4F1 | HEXA, ST6GALNAC4 | More | | | Colchiceine | hsa00630 | Glyoxylate and dicarboxylate metabolism | 2.42E-02 | 2 | P40925, P15104 | MDH1, GLUL | More | | | Colchiceine | hsa00730 | Thiamine metabolism | 5.29E-03 | 2 | P05186, P24666 | ALPL, ACP1 | More | | | Colchiceine | hsa00770 | Pantothenate and CoA biosynthesis | 1.15E-02 | 2 | O95498, Q9NRN7 | VNN2, AASDHPPT | More | | | Colchiceine | hsa00830 | Retinol metabolism | 3.93E-02 | 3 | P00352, Q9BPW9, O75911 | ALDH1A1, DHRS9, DHRS3 | More | | | Colchiceine | hsa00860 | Porphyrin and chlorophyll metabolism | 1.69E-02 | 2 | P36551, P30043 | CPOX, BLVRB | More | | | Colchiceine | hsa00983 | Drug metabolism - other enzymes | 2.44E-02 | 2 | P32320, P05164 | CDA, MPO | More | | | Colchiceine | hsa01200 | Carbon metabolism | 1.99E-02 | 2 | P06744, P60174 | GPI, TPI1 | More | | | Colchiceine | hsa01230 | Biosynthesis of amino acids | 3.59E-02 | 3 | P60891, Q99707, P37837 | PRPS1, MTR, TALDO1 | More | | | Colchiceine | hsa01521 | EGFR tyrosine kinase inhibitor resistance | 2.90E-02 | 3 | P17252, P10415, Q9NRA1 | PRKCA, BCL2, PDGFC | More | | | Colchiceine | hsa01524 | Platinum drug resistance | 4.02E-02 | 4 | Q13315, P10415, Q13489, P43246 | ATM, BCL2, BIRC3, MSH2 | More | | | Colchiceine | hsa03008 | Ribosome biogenesis in eukaryotes | 1.88E-02 | 3 | O14980, O60832, Q9BVP2 | XPO1, DKC1, GNL3 | More | | | Colchiceine | hsa03013 | RNA transport | 7.33E-06 | 12 | O14980, P52298, O14893, P61326, Q7Z3B4, P35658, Q14152, O75822, P78345, Q14240, P23588, Q9Y6A5 | XPO1, NCBP2, GEMIN2, MAGOH, NUP54, NUP214, EIF3A, EIF3J, RPP38, EIF4A2, EIF4B, TACC3 | More | | | Colchiceine | hsa03040 | Spliceosome | 1.45E-04 | 11 | Q14562, O43143, O60508, P26368, P52298, Q13595, Q07955, Q01130, P84103, Q13243, P11142 | DHX8, DHX15, CDC40, U2AF2, NCBP2, TRA2A, SFRS1, SFRS2, SFRS3, SFRS5, HSPA8 | More | | | Colchiceine | hsa03050 | Proteasome | 4.83E-02 | 1 | P55036 | PSMD4 | More | | | Colchiceine | hsa04020 | Calcium signaling pathway | 2.09E-02 | 5 | Q16566, P17252, P25116, P0DP23, Q9NRA1 | CAMK4, PRKCA, F2R, CALM1, PDGFC | More | | | Colchiceine | hsa04060 | Cytokine-cytokine receptor interaction | 5.34E-03 | 11 | P14784, P27930, P14778, P26842, Q06643, Q13651, P25024, Q9UBD3, P47992, P09341, P01730 | IL2RB, IL1R2, IL1R1, CD27, LTB, IL10RA, CXCR1, XCL2, XCL1, CXCL1, CD4 | More | | | Colchiceine | hsa04061 | Viral protein interaction with cytokine and cytokine receptor | 1.70E-03 | 8 | P09341, P19875, P25024, P25025, P47992, Q9UBD3, Q13651, P14784 | CXCL1, CXCL2, CXCR1, CXCR2, XCL1, XCL2, IL10RA, IL2RB | More | | | Colchiceine | hsa04062 | Chemokine signaling pathway | 4.01E-04 | 13 | P25024, P25025, P09341, P19875, P47992, Q9UBD3, P07948, P42338, P19174, P63218, P50151, P43250, Q08881 | CXCR1, CXCR2, CXCL1, CXCL2, XCL1, XCL2, LYN, PIK3CB, PLCG1, GNG5, GNG10, GRK6, ITK | More | | | Colchiceine | hsa04064 | NF-kappa B signaling pathway | 3.66E-08 | 21 | P10415, Q13489, P25963, P51617, O00463, Q13546, P14778, P19174, Q04759, Q9UDY8, Q13077, Q16548, P07948, P06239, Q13315, P24522, O75293, P09341, P19875, Q06643, Q9UNE0 | BCL2, BIRC3, NFKBIA, IRAK1, TRAF5, RIPK1, IL1R1, PLCG1, PRKCQ, MALT1, TRAF1, BCL2A1, LYN, LCK, ATM, GADD45A, GADD45B, CXCL1, CXCL2, LTB, EDAR | More | | Genes in community(ComG) | Gene name of ComG | Protein name of ComG | Co-expressed genes in pathway (PathG) | Gene name of PathG | Protein name of PathG | Coexpression |
|---|
| P68371 | TUBB2C | Tubulin beta-4B chain | P10415 | BCL2 | Apoptosis regulator Bcl-2 | -0.766 | | Q13509 | TUBB3 | Tubulin beta-3 chain | P10415 | BCL2 | Apoptosis regulator Bcl-2 | -0.809 | | P09958 | FURIN | Furin | P10415 | BCL2 | Apoptosis regulator Bcl-2 | -0.806 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | 0.868 | | P68371 | TUBB2C | Tubulin beta-4B chain | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | -0.892 | | Q13509 | TUBB3 | Tubulin beta-3 chain | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | -0.716 | | P09958 | FURIN | Furin | Q13489 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | -0.714 | | Q13509 | TUBB3 | Tubulin beta-3 chain | P25963 | NFKBIA | NF-kappa-B inhibitor alpha | 0.714 | | Q13509 | TUBB3 | Tubulin beta-3 chain | P51617 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | -0.757 | | P06239 | LCK | Tyrosine-protein kinase Lck | O00463 | TRAF5 | TNF receptor-associated factor 5 | 0.718 | | P09958 | FURIN | Furin | O00463 | TRAF5 | TNF receptor-associated factor 5 | -0.749 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | -0.749 | | P68371 | TUBB2C | Tubulin beta-4B chain | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | 0.748 | | Q13509 | TUBB3 | Tubulin beta-3 chain | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | 0.735 | | P09958 | FURIN | Furin | Q13546 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | 0.776 | | P06239 | LCK | Tyrosine-protein kinase Lck | P14778 | IL1R1 | Interleukin-1 receptor type 1 | -0.782 | | Q13547 | HDAC1 | Histone deacetylase 1 | P14778 | IL1R1 | Interleukin-1 receptor type 1 | -0.854 | | Q13547 | HDAC1 | Histone deacetylase 1 | P19174 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 0.7 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q04759 | PRKCQ | Protein kinase C theta type | 0.779 | | Q13547 | HDAC1 | Histone deacetylase 1 | Q04759 | PRKCQ | Protein kinase C theta type | 0.723 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | 0.708 | | P68371 | TUBB2C | Tubulin beta-4B chain | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | -0.783 | | Q13509 | TUBB3 | Tubulin beta-3 chain | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | -0.846 | | P09958 | FURIN | Furin | Q9UDY8 | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | -0.865 | | P09958 | FURIN | Furin | Q13077 | TRAF1 | TNF receptor-associated factor 1 | -0.741 | | P09958 | FURIN | Furin | Q16548 | BCL2A1 | Bcl-2-related protein A1 | 0.793 | | P06239 | LCK | Tyrosine-protein kinase Lck | P07948 | LYN | Tyrosine-protein kinase Lyn | -0.701 | | P06239 | LCK | Tyrosine-protein kinase Lck | P06239 | LCK | Tyrosine-protein kinase Lck | 1 | | Q13547 | HDAC1 | Histone deacetylase 1 | P06239 | LCK | Tyrosine-protein kinase Lck | 0.811 | | P68371 | TUBB2C | Tubulin beta-4B chain | Q13315 | ATM | Serine-protein kinase ATM | -0.772 | | P06239 | LCK | Tyrosine-protein kinase Lck | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | -0.724 | | P09958 | FURIN | Furin | P24522 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | 0.806 | | Q13509 | TUBB3 | Tubulin beta-3 chain | O75293 | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta | -0.826 | | P06239 | LCK | Tyrosine-protein kinase Lck | P09341 | CXCL1 | Growth-regulated alpha protein | -0.805 | | Q13547 | HDAC1 | Histone deacetylase 1 | P09341 | CXCL1 | Growth-regulated alpha protein | -0.736 | | Q13547 | HDAC1 | Histone deacetylase 1 | P19875 | CXCL2 | C-X-C motif chemokine 2 | -0.862 | | P06239 | LCK | Tyrosine-protein kinase Lck | Q06643 | LTB | Lymphotoxin-beta | 0.846 | | Q13547 | HDAC1 | Histone deacetylase 1 | Q06643 | LTB | Lymphotoxin-beta | 0.74 | | P08235 | NR3C2 | Mineralocorticoid receptor | Q9UNE0 | EDAR | Tumor necrosis factor receptor superfamily member EDAR | 0.819 |
| | Colchiceine | hsa04071 | Sphingolipid signaling pathway | 4.60E-05 | 10 | P17252, P21453, Q9H228, P01375, Q16537, Q9BX95, Q16539, P10415, Q9UQC2, P01042 | PRKCA, S1PR1, EDG8, TNF, PPP2R5E, SGPP1, MAPK14, BCL2, GAB2, KNG1 | More | | | Colchiceine | hsa04072 | Phospholipase D signaling pathway | 1.54E-03 | 10 | P42338, P43657, P25116, P25024, P25025, P19174, P17252, O14494, P23743, Q9NRA1 | PIK3CB, P2RY5, F2R, CXCR1, CXCR2, PLCG1, PRKCA, PLPP1, DGKA, PDGFC | More | | | Colchiceine | hsa04114 | Oocyte meiosis | 2.05E-02 | 5 | Q9Y6D9, P51812, Q02750, P16298, Q17RY0 | MAD1L1, RPS6KA3, MAP2K1, PPP3CB, CPEB4 | More | | | Colchiceine | hsa04120 | Ubiquitin mediated proteolysis | 3.44E-02 | 4 | Q14145, Q13042, P62837, Q15751 | KEAP1, CDC16, UBE2D2, HERC1 | More | | | Colchiceine | hsa04136 | Autophagy - other | 5.92E-03 | 2 | O94817, Q9H1Y0 | ATG12, ATG5 | More | | | Colchiceine | hsa04141 | Protein processing in endoplasmic reticulum | 2.77E-02 | 5 | P27824, P30101, P60604, P11142, P08238 | CANX, PDIA3, UBE2G2, HSPA8, HSP90AB1 | More | | | Colchiceine | hsa04145 | Phagosome | 2.46E-03 | 6 | Q15080, P14598, Q13509, P68371, Q13488, P27824 | NCF4, NCF1, TUBB3, TUBB2C, TCIRG1, CANX | More | | | Colchiceine | hsa04210 | Apoptosis | 3.58E-02 | 4 | O76075, P01375, Q9NR28, Q16548 | DFFB, TNF, DIABLO, BCL2A1 | More | | | Colchiceine | hsa04211 | Longevity regulating pathway | 1.18E-02 | 3 | Q12778, Q9UEF7, Q96KQ7 | FOXO1, KL, EHMT2 | More | | | Colchiceine | hsa04213 | Longevity regulating pathway - multiple species | 3.85E-02 | 4 | P42338, Q9Y4H2, P11142, Q13547 | PIK3CB, IRS2, HSPA8, HDAC1 | More | | | Colchiceine | hsa04217 | Necroptosis | 3.55E-07 | 12 | P01375, P01568, P48023, Q13489, Q13546, P42224, Q14765, P08238, Q6FI13, Q99878, P10415, O43633 | TNF, IFNA21, FASLG, BIRC3, RIPK1, STAT1, STAT4, HSP90AB1, H2AC18; H2AC19, H2AC14, BCL2, CHMP2A | More | | | Colchiceine | hsa04340 | Hedgehog signaling pathway | 3.32E-02 | 2 | P49841, P22694 | GSK3B, PRKACB | More | | | Colchiceine | hsa04370 | VEGF signaling pathway | 1.29E-02 | 3 | P16298, Q05397, Q02750 | PPP3CB, PTK2, MAP2K1 | More | | | Colchiceine | hsa04371 | Apelin signaling pathway | 1.12E-03 | 9 | P62873, P63218, P50151, Q13370, Q14344, Q13485, P84022, Q16566, P0DP23 | GNB1, GNG5, GNG10, PDE3B, GNA13, SMAD4, SMAD3, CAMK4, CALM1 | More | | | Colchiceine | hsa04520 | Adherens junction | 8.77E-03 | 4 | Q13485, P84022, O95863, Q15223 | SMAD4, SMAD3, SNAI1, PVRL1 | More | | | Colchiceine | hsa04540 | Gap junction | 5.44E-03 | 4 | P17252, Q13509, P68371, Q9NRA1 | PRKCA, TUBB3, TUBB2C, PDGFC | More | | | Colchiceine | hsa04612 | Antigen processing and presentation | 1.75E-02 | 6 | P13765, P01730, P26715, P26717, Q13241, P01732 | HLA-DOB, CD4, KLRC1, KLRC2, KLRD1, CD8A | More | | | Colchiceine | hsa04613 | Neutrophil extracellular trap formation | 7.45E-03 | 12 | O60603, P05164, P08246, Q9UM07, Q92769, Q6FI13, Q15080, O75015, P21730, P21462, O43315, Q16539 | TLR2, MPO, ELA2, PADI4, HDAC2, H2AC18; H2AC19, NCF4, FCGR3B, C5AR1, FPR1, AQP9, MAPK14 | More | | | Colchiceine | hsa04620 | Toll-like receptor signaling pathway | 9.62E-04 | 5 | P51617, Q13546, P01568, P42224, P25963 | IRAK1, RIPK1, IFNA21, STAT1, NFKBIA | More | | | Colchiceine | hsa04621 | NOD-like receptor signaling pathway | 8.07E-03 | 7 | P08238, P42224, P01568, P25963, Q13489, P10415, Q13546 | HSP90AB1, STAT1, IFNA21, NFKBIA, BIRC3, BCL2, RIPK1 | More | | | Colchiceine | hsa04622 | RIG-I-like receptor signaling pathway | 2.39E-02 | 2 | P01568, Q13546 | IFNA21, RIPK1 | More | | | Colchiceine | hsa04623 | Cytosolic DNA-sensing pathway | 3.48E-07 | 3 | P01568, Q13546, P25963 | IFNA21, RIPK1, NFKBIA | More | | | Colchiceine | hsa04640 | Hematopoietic cell lineage | 1.03E-05 | 11 | P13612, P14778, P27930, P11215, P25063, P07766, P09693, P01732, P01730, P09564, P13765 | ITGA4, IL1R1, IL1R2, ITGAM, CD24, CD3E, CD3G, CD8A, CD4, CD7, HLA-DOB | More | | | Colchiceine | hsa04650 | Natural killer cell mediated cytotoxicity | 2.48E-05 | 10 | P19174, P06239, O60880, P20963, P42338, Q13241, P26718, O14931, P26717, P26715 | PLCG1, LCK, SH2D1A, CD247, PIK3CB, KLRD1, KLRK1, NCR3, KLRC2, KLRC1 | More | | | Colchiceine | hsa04657 | IL-17 signaling pathway | 3.31E-02 | 3 | P49841, P14780, P01375 | GSK3B, MMP9, TNF | More | | | Colchiceine | hsa04658 | Th1 and Th2 cell differentiation | 2.82E-10 | 12 | Q04759, P07766, P20963, P09693, P19174, P01730, P06239, P23771, Q9UL17, P14784, P13765, Q13761 | PRKCQ, CD3E, CD247, CD3G, PLCG1, CD4, LCK, GATA3, TBX21, IL2RB, HLA-DOB, RUNX3 | More | | | Colchiceine | hsa04659 | Th17 cell differentiation | 4.34E-09 | 15 | Q04759, P19174, P01730, P06239, P14784, P13765, P14778, Q9UL17, P23771, P84022, Q13485, P08238, P07766, P09693, P20963 | PRKCQ, PLCG1, CD4, LCK, IL2RB, HLA-DOB, IL1R1, TBX21, GATA3, SMAD3, SMAD4, HSP90AB1, CD3E, CD3G, CD247 | More | | | Colchiceine | hsa04660 | T cell receptor signaling pathway | 1.03E-05 | 11 | Q04759, P42338, Q08881, P19174, P07766, P20963, P09693, P01730, P01732, Q13191, P06239 | PRKCQ, PIK3CB, ITK, PLCG1, CD3E, CD247, CD3G, CD4, CD8A, CBLB, LCK | More | | | Colchiceine | hsa04664 | Fc epsilon RI signaling pathway | 2.35E-02 | 3 | P07948, P19174, P09917 | LYN, PLCG1, ALOX5 | More | | | Colchiceine | hsa04666 | Fc gamma R-mediated phagocytosis | 2.81E-02 | 4 | P23528, O14494, P14598, P17252 | CFL1, PLPP1, NCF1, PRKCA | More | | | Colchiceine | hsa04668 | TNF signaling pathway | 4.96E-02 | 6 | O00463, Q13546, Q13489, Q16539, Q13077, P14780 | TRAF5, RIPK1, BIRC3, MAPK14, TRAF1, MMP9 | More | | | Colchiceine | hsa04710 | Circadian rhythm | 1.79E-02 | 1 | O15516 | CLOCK | More | | | Colchiceine | hsa04720 | Long-term potentiation | 2.05E-02 | 3 | P17252, Q16566, P0DP23 | PRKCA, CAMK4, CALM1 | More | | | Colchiceine | hsa04722 | Neurotrophin signaling pathway | 3.27E-02 | 3 | P49841, O43524, P48023 | GSK3B, FOXO3, FASLG | More | | | Colchiceine | hsa04724 | Glutamatergic synapse | 4.43E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Colchiceine | hsa04725 | Cholinergic synapse | 8.04E-03 | 4 | P17252, P62873, Q16566, P10415 | PRKCA, GNB1, CAMK4, BCL2 | More | | | Colchiceine | hsa04727 | GABAergic synapse | 4.43E-02 | 3 | P63218, P50151, P15104 | GNG5, GNG10, GLUL | More | | | Colchiceine | hsa04744 | Phototransduction | 8.61E-05 | 2 | P62873, P0DP23 | GNB1, CALM1 | More | | | Colchiceine | hsa04750 | Inflammatory mediator regulation of TRP channels | 7.24E-03 | 5 | P14778, P19174, P42338, P24723, Q04759 | IL1R1, PLCG1, PIK3CB, PRKCH, PRKCQ | More | | | Colchiceine | hsa04910 | Insulin signaling pathway | 2.35E-02 | 3 | P22694, P06737, P49841 | PRKACB, PYGL, GSK3B | More | | | Colchiceine | hsa04914 | Progesterone-mediated oocyte maturation | 2.66E-02 | 4 | Q17RY0, Q9Y6D9, P51812, Q02750 | CPEB4, MAD1L1, RPS6KA3, MAP2K1 | More | | | Colchiceine | hsa04916 | Melanogenesis | 2.90E-02 | 3 | P0DP23, Q9UJU2, P17252 | CALM1, LEF1, PRKCA | More | | | Colchiceine | hsa04919 | Thyroid hormone signaling pathway | 7.11E-03 | 4 | P49841, P22694, O60244, Q9NVC6 | GSK3B, PRKACB, MED14, MED17 | More | | | Colchiceine | hsa04923 | Regulation of lipolysis in adipocytes | 2.24E-02 | 3 | P07550, P42338, Q9Y4H2 | ADRB2, PIK3CB, IRS2 | More | | | Colchiceine | hsa04925 | Aldosterone synthesis and secretion | 3.91E-02 | 3 | P0DP23, P17252, Q16566 | CALM1, PRKCA, CAMK4 | More | | | Colchiceine | hsa04931 | Insulin resistance | 1.94E-02 | 3 | P01375, P49841, P06737 | TNF, GSK3B, PYGL | More | | | Colchiceine | hsa04932 | Non-alcoholic fatty liver disease | 2.74E-02 | 3 | P01375, P49841, P48023 | TNF, GSK3B, FASLG | More | | | Colchiceine | hsa04940 | Type I diabetes mellitus | 1.87E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | | Colchiceine | hsa04961 | Endocrine and other factor-regulated calcium reabsorption | 1.22E-02 | 3 | P20020, Q9UEF7, P17252 | ATP2B1, KL, PRKCA | More | | | Colchiceine | hsa04973 | Carbohydrate digestion and absorption | 1.29E-02 | 2 | O43451, P42338 | MGAM, PIK3CB | More | | | Colchiceine | hsa04975 | Fat digestion and absorption | 2.80E-02 | 1 | O14494 | PLPP1 | More | | | Colchiceine | hsa04976 | Bile secretion | 2.44E-02 | 2 | P22694, P08183 | PRKACB, ABCB1 | More | | | Colchiceine | hsa05032 | Morphine addiction | 4.43E-02 | 3 | P63218, P50151, P43250 | GNG5, GNG10, GRK6 | More | | | Colchiceine | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | 2.78E-03 | 5 | P09341, P19875, P19174, P25024, P25025 | CXCL1, CXCL2, PLCG1, CXCR1, CXCR2 | More | | | Colchiceine | hsa05132 | Salmonella infection | 8.17E-07 | 12 | P51617, P25963, P08238, Q9UJU2, Q13546, Q13489, P10415, O75369, Q13561, O60282, Q13509, P68371 | IRAK1, NFKBIA, HSP90AB1, LEF1, RIPK1, BIRC3, BCL2, FLNB, DCTN2, KIF5C, TUBB3, TUBB2C | More | | | Colchiceine | hsa05134 | Legionellosis | 1.29E-02 | 4 | P11215, P11142, P09341, P19875 | ITGAM, HSPA8, CXCL1, CXCL2 | More | | | Colchiceine | hsa05140 | Leishmaniasis | 4.05E-03 | 6 | P14598, P42224, P25963, P29350, P51617, Q15080 | NCF1, STAT1, NFKBIA, PTPN6, IRAK1, NCF4 | More | | | Colchiceine | hsa05143 | African trypanosomiasis | 2.72E-02 | 2 | P01375, P48023 | TNF, FASLG | More | | | Colchiceine | hsa05145 | Toxoplasmosis | 1.95E-02 | 6 | P51617, P25963, P10415, Q13489, P42224, P11142 | IRAK1, NFKBIA, BCL2, BIRC3, STAT1, HSPA8 | More | | | Colchiceine | hsa05146 | Amoebiasis | 8.66E-06 | 9 | P09341, P19875, P14778, P27930, P42338, P11215, P05089, P12814, P08311 | CXCL1, CXCL2, IL1R1, IL1R2, PIK3CB, ITGAM, ARG1, ACTN1, CTSG | More | | | Colchiceine | hsa05152 | Tuberculosis | 6.22E-04 | 8 | Q13488, P0DP23, P42224, P25208, P10415, P01568, Q9UDY8, P51617 | TCIRG1, CALM1, STAT1, NFYB, BCL2, IFNA21, MALT1, IRAK1 | More | | | Colchiceine | hsa05160 | Hepatitis C | 1.27E-02 | 4 | P60033, P49841, P01375, P48023 | CD81, GSK3B, TNF, FASLG | More | | | Colchiceine | hsa05162 | Measles | 4.50E-03 | 8 | P51617, P01568, P25963, P42224, P14784, P10747, P11142, P10415 | IRAK1, IFNA21, NFKBIA, STAT1, IL2RB, CD28, HSPA8, BCL2 | More | | | Colchiceine | hsa05166 | Human T-cell leukemia virus 1 infection | 1.77E-02 | 8 | P27824, P30279, P21796, P84022, Q13485, P07766, Q92830, P06746 | CANX, CCND2, VDAC1, SMAD3, SMAD4, CD3E, KAT2A, POLB | More | | | Colchiceine | hsa05168 | Herpes simplex virus 1 infection | 5.65E-04 | 14 | P25963, P01568, P42224, Q07955, Q01130, Q13243, Q13489, P51617, Q13398, Q9NR11, P17097, P17038, Q03923, P10415 | NFKBIA, IFNA21, STAT1, SFRS1, SFRS2, SFRS5, BIRC3, IRAK1, ZNF211, ZNF302, ZNF7, ZNF43, ZNF85, BCL2 | More | | | Colchiceine | hsa05169 | Epstein-Barr virus infection | 4.84E-03 | 10 | P13765, P01106, Q13547, O00463, P07948, Q13761, P24522, P07766, P09693, P20963 | HLA-DOB, MYC, HDAC1, TRAF5, LYN, RUNX3, GADD45A, CD3E, CD3G, CD247 | More | | | Colchiceine | hsa05170 | Human immunodeficiency virus 1 infection | 3.95E-05 | 11 | P62873, P0DP23, P17252, Q13546, P01568, P51617, P25963, Q13315, P23528, P10415, Q9Y6Q5 | GNB1, CALM1, PRKCA, RIPK1, IFNA21, IRAK1, NFKBIA, ATM, CFL1, BCL2, AP1M2 | More | | | Colchiceine | hsa05200 | Pathways in cancer | 2.19E-05 | 27 | P04628, Q13751, P08238, P42224, P25963, P19174, Q9UJU2, P17252, P43246, P84022, Q13485, P20585, P14923, P30279, P10415, Q13489, Q12778, P25116, P62873, P63218, P50151, Q14344, O75293, P0DP23, P01568, P14784, P01042 | WNT1, LAMB3, HSP90AB1, STAT1, NFKBIA, PLCG1, LEF1, PRKCA, MSH2, SMAD3, SMAD4, MSH3, JUP, CCND2, BCL2, BIRC3, FOXO1, F2R, GNB1, GNG5, GNG10, GNA13, GADD45B, CALM1, IFNA21, IL2RB, KNG1 | More | | | Colchiceine | hsa05202 | Transcriptional misregulation in cancer | 1.61E-03 | 13 | Q15532, P41732, P14780, P27930, Q16548, Q13489, Q13077, P35226, P05164, P08246, Q9C0K0, Q92769, P24522 | SS18, TSPAN7, MMP9, IL1R2, BCL2A1, BIRC3, TRAF1, BMI1, MPO, ELA2, BCL11B, HDAC2, GADD45A | More | | | Colchiceine | hsa05203 | Viral carcinogenesis | 1.90E-02 | 6 | P06746, Q92830, P07948, P30279, P29083, Q93079 | POLB, KAT2A, LYN, CCND2, GTF2E1, H2BC9 | More | | | Colchiceine | hsa05214 | Glioma | 2.90E-02 | 3 | P0DP23, Q16566, P17252 | CALM1, CAMK4, PRKCA | More | | | Colchiceine | hsa05215 | Prostate cancer | 6.15E-03 | 5 | P10415, Q9UJU2, Q12778, Q9NRA1, P08238 | BCL2, LEF1, FOXO1, PDGFC, HSP90AB1 | More | | | Colchiceine | hsa05217 | Basal cell carcinoma | 2.01E-02 | 4 | Q13635, P04628, Q9UJU2, P24522 | PTCH1, WNT1, LEF1, GADD45A | More | | | Colchiceine | hsa05231 | Choline metabolism in cancer | 5.44E-03 | 4 | Q9NRA1, P23743, O14494, P17252 | PDGFC, DGKA, PLPP1, PRKCA | More | | | Colchiceine | hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 2.33E-04 | 8 | P42338, P19174, P07766, P20963, P09693, P06239, Q04759, P01730 | PIK3CB, PLCG1, CD3E, CD247, CD3G, LCK, PRKCQ, CD4 | More | | | Colchiceine | hsa05330 | Allograft rejection | 2.72E-02 | 2 | P48023, P01375 | FASLG, TNF | More | | | Colchiceine | hsa05332 | Graft-versus-host disease | 3.75E-03 | 5 | P13765, P48023, P01375, P26715, Q13241 | HLA-DOB, FASLG, TNF, KLRC1, KLRD1 | More | | | Colchiceine | hsa05340 | Primary immunodeficiency | 2.19E-02 | 4 | P01730, P01732, P07766, P06239 | CD4, CD8A, CD3E, LCK | More | |
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