| 1998 | [Treatment of newly diagnosed patients with infiltrative and disseminated pulmonary tuberculosis]. | Probl Tuberk | To enhance the efficiency of treatment in new cases of infiltrative and disseminated destructive pulmonary tuberculosis, an intermittent (twice daily) regimen of intravenous dropwise administration of three drugs (isoniazid, rifampicin, PASK) was proposed. The immediate results of clinical observations suggest that intermittent 3-drug intravenous chemotherapy supplemented by collapse therapy in some indicated cases, provides a high control over the therapy, sparing drug load, good tolerance, and rather high efficiency: elimination of destructions in 81.4% (mean 4.2 months), cessation of bacterial isolation in 88.9% in the early (2.2 months) period. |