Compound Information


Test on : DRx, RBC, Metz

Compound Name
DRx, RBC, Metz : Imatinib

Inchikey
Same : KTUFNOKKBVMGRW-N
DRx, RBC, Metz : KTUFNOKKBVMGRW-UHFFFAOYSA-N

ChemSpider
DRx, RBC, Metz : 5101

Pubchem CID
DRx, RBC, Metz : 5291

ChEMBL
DRx, RBC, Metz : CHEMBL941




DRx RBC Metz Millipore GPCR
bioactivity Kd (nM) Remain Activity (%) Ki (nM) Remain Activity (%) Inhibition (%)
active criteria <3000nM <50% <1000nM <50% >50%

Other


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
441-
3332
2221
42--
21--
4444
11982
3311
4433
111-
32--
21--
543-
221-
111-
1-1-
1-11
4-2-
1--1
Other - NAK

Bioactivity
KinaseDRxRBCMetz
AAK1inactive (10001nM)--
BIKEinactive (10001nM)--
GAKactive (1000nM)--
MPSK1inactive (10001nM)inactive (102.81%)-
Other - Aur

Bioactivity
KinaseDRxRBCMetz
AurAinactive (10001nM)inactive (98.24%)inactive (>2511.89nM)
AurBinactive (10001nM)inactive (97.17%)inactive (>5011.87nM)
AurCinactive (10001nM)inactive (118.73%)-
Other - CAMKK

Bioactivity
KinaseDRxRBCMetz
CaMKK1inactive (10001nM)inactive (96.37%)-
CaMKK2inactive (10001nM)inactive (97.53%)inactive (>2511.89nM)
Other - PEK

Bioactivity
KinaseDRxRBCMetz
HRIinactive (10001nM)--
PKRinactive (10001nM)--
Other - IRE

Bioactivity
KinaseDRxRBCMetz
IRE1inactive (10001nM)--
Other - IKK

Bioactivity
KinaseDRxRBCMetz
IKKainactive (10001nM)inactive (98.8%)inactive (>3981.07nM)
IKKbinactive (10001nM)inactive (85.87%)inactive (>3162.28nM)
IKKeinactive (10001nM)inactive (89.3%)inactive (>3162.28nM)
TBK1inactive (10001nM)inactive (96.73%)inactive (>3162.28nM)
Other - NEK

Bioactivity
KinaseDRxRBCMetz
NEK1inactive (10001nM)inactive (124.66%)-
NEK11inactive (10001nM)inactive (110.22%)-
NEK2inactive (10001nM)inactive (98.7%)inactive (>7943.28nM)
NEK3inactive (10001nM)inactive (96.99%)-
NEK4inactive (10001nM)inactive (98.2%)inactive (>6309.57nM)
NEK5inactive (10001nM)--
NEK6inactive (10001nM)inactive (97.95%)-
NEK7inactive (10001nM)inactive (101.65%)-
NEK9inactive (10001nM)inactive (99.58%)-
Other - WEE

Bioactivity
KinaseDRxRBCMetz
MYT1inactive (10001nM)--
Wee1inactive (10001nM)inactive (100.53%)-
Wee1Binactive (10001nM)--
Other - PLK

Bioactivity
KinaseDRxRBCMetz
PLK1inactive (10001nM)inactive (100.3%)inactive (>7943.28nM)
PLK2inactive (10001nM)inactive (103.96%)-
PLK3inactive (10001nM)inactive (100.02%)inactive (>7943.28nM)
PLK4inactive (7800nM)-inactive (>3162.28nM)
Other - SgK496

Bioactivity
KinaseDRxRBCMetz
SgK496inactive (10001nM)inactive (97.66%)-
Other - NKF1

Bioactivity
KinaseDRxRBCMetz
SBKinactive (10001nM)--
SgK110inactive (10001nM)--
Other - NKF4

Bioactivity
KinaseDRxRBCMetz
CLIK1inactive (10001nM)--
Other - ULK

Bioactivity
KinaseDRxRBCMetz
Fusedinactive (10001nM)--
ULK1inactive (10001nM)inactive (93.58%)-
ULK2inactive (10001nM)inactive (102.54%)-
ULK3inactive (10001nM)inactive (108.24%)-
Other - TLK

Bioactivity
KinaseDRxRBCMetz
TLK1inactive (10001nM)--
TLK2inactive (10001nM)inactive (78.41%)-
Other - TTK

Bioactivity
KinaseDRxRBCMetz
TTKinactive (10001nM)inactive (102.42%)-
Other - Haspin

Bioactivity
KinaseDRxRBCMetz
Haspin-inactive (92.73%)-
Other - TOPK

Bioactivity
KinaseDRxRBCMetz
PBK-inactive (100.77%)inactive (>10000nM)
Other - WNK

Bioactivity
KinaseDRxRBCMetz
Wnk2-inactive (102.33%)-
Wnk3-inactive (99.38%)-
Other - CDC7

Bioactivity
KinaseDRxRBCMetz
CDC7--inactive (>1258.93nM)

TK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
2221
2222
3332
1111119
5553
5555
2221
221-
4433
1413121
2222
2222
4442
3333
3332
4443
2222
111-
1111
1111
2221
221-
2211
3333
TK - Abl

Bioactivity
KinaseDRxRBCMetz
ABL1active (1.1nM)active (44.3%)active (50.12nM)
ABL2active (10nM)inactive (55.91%)-
TK - ALK

Bioactivity
KinaseDRxRBCMetz
ALKinactive (10001nM)inactive (95.07%)inactive (>5011.87nM)
LTKinactive (10001nM)inactive (100.11%)inactive (>2511.89nM)
TK - Axl

Bioactivity
KinaseDRxRBCMetz
AXLinactive (10001nM)inactive (90.47%)inactive (>1995.26nM)
MERinactive (10001nM)inactive (91.05%)-
TYRO3inactive (10001nM)inactive (93.68%)inactive (>2511.89nM)
TK - Src

Bioactivity
KinaseDRxRBCMetz
BLKactive (520nM)inactive (89.04%)inactive (>1000nM)
BRKinactive (10001nM)inactive (93.62%)inactive (>2511.89nM)
FGRactive (2400nM)inactive (80.06%)-
FRKactive (1500nM)inactive (93.81%)active (316.23nM)
FYNinactive (3100nM)inactive (85.84%)inactive (>3981.07nM)
HCKinactive (10001nM)inactive (84.95%)inactive (>3162.28nM)
LCKactive (40nM)active (30.91%)active (316.23nM)
LYNactive (890nM)inactive (59.63%)active (199.53nM)
SRCinactive (10001nM)inactive (86.46%)inactive (>3981.07nM)
SRMinactive (10001nM)inactive (100.1%)inactive (>1584.89nM)
YESinactive (10001nM)inactive (88.59%)-
TK - Tec

Bioactivity
KinaseDRxRBCMetz
BMXinactive (10001nM)inactive (99.52%)-
BTKinactive (10001nM)inactive (102.64%)inactive (>5011.87nM)
ITKinactive (10001nM)inactive (98.2%)inactive (>1584.89nM)
TECinactive (10001nM)inactive (94.89%)-
TXKinactive (10001nM)inactive (108%)-
TK - PDGFR

Bioactivity
KinaseDRxRBCMetz
FMSactive (11nM)active (15.34%)active (158.49nM)
FLT3inactive (10001nM)inactive (90.5%)inactive (>2511.89nM)
KITactive (13nM)active (49.56%)inactive (>3981.07nM)
PDGFRaactive (31nM)active (5.9%)active (158.49nM)
PDGFRbactive (14nM)active (39.11%)active (50.12nM)
TK - Csk

Bioactivity
KinaseDRxRBCMetz
CSKinactive (10001nM)inactive (92.14%)-
CTKinactive (10001nM)inactive (94.93%)inactive (>1995.26nM)
TK - DDR

Bioactivity
KinaseDRxRBCMetz
DDR1active (0.7nM)--
DDR2active (15nM)active (27.07%)-
TK - EGFR

Bioactivity
KinaseDRxRBCMetz
EGFRinactive (10001nM)inactive (92.03%)inactive (>1995.26nM)
ErbB2inactive (10001nM)inactive (104.62%)inactive (>1584.89nM)
ErbB3inactive (10001nM)--
ErbB4inactive (10001nM)inactive (92.24%)inactive (>3981.07nM)
TK - Eph

Bioactivity
KinaseDRxRBCMetz
EphA1inactive (10001nM)inactive (99.9%)-
EphA2inactive (10001nM)inactive (87.15%)inactive (>3162.28nM)
EphA3inactive (10001nM)inactive (99.54%)-
EphA4inactive (10001nM)inactive (107.53%)-
EphA5inactive (10001nM)inactive (103.65%)-
EphA6inactive (10001nM)inactive (100.01%)-
EphA7inactive (10001nM)inactive (98.78%)-
EphA8active (1400nM)inactive (94.74%)-
EphB1inactive (10001nM)inactive (101.75%)-
EphB2inactive (10001nM)inactive (95.82%)-
EphB3inactive (10001nM)inactive (72.39%)-
EphB4inactive (10001nM)inactive (95.06%)-
EphB6inactive (10001nM)--
TK - FAK

Bioactivity
KinaseDRxRBCMetz
FAKinactive (10001nM)inactive (94.95%)inactive (>5011.87nM)
PYK2inactive (10001nM)inactive (100.65%)inactive (>1584.89nM)
TK - Fer

Bioactivity
KinaseDRxRBCMetz
FERinactive (10001nM)inactive (94.35%)inactive (>1584.89nM)
FESinactive (10001nM)inactive (101.01%)inactive (>1995.26nM)
TK - FGFR

Bioactivity
KinaseDRxRBCMetz
FGFR1inactive (10001nM)inactive (102.52%)inactive (>3981.07nM)
FGFR2inactive (10001nM)inactive (100.27%)-
FGFR3inactive (10001nM)inactive (97.4%)inactive (>1995.26nM)
FGFR4inactive (10001nM)inactive (96.34%)-
TK - VEGFR

Bioactivity
KinaseDRxRBCMetz
FLT1inactive (10001nM)inactive (98.28%)inactive (>3162.28nM)
FLT4inactive (10001nM)inactive (98.87%)inactive (>6309.57nM)
KDRinactive (10001nM)inactive (94.24%)inactive (>3162.28nM)
TK - InsR

Bioactivity
KinaseDRxRBCMetz
IGF1Rinactive (10001nM)inactive (95.75%)inactive (>1995.26nM)
INSRinactive (10001nM)inactive (108.78%)inactive (>5011.87nM)
IRRinactive (10001nM)inactive (107.69%)-
TK - JakA

Bioactivity
KinaseDRxRBCMetz
JAK1inactive (10001nM)inactive (100.33%)-
JAK2inactive (10001nM)inactive (97.76%)inactive (>1995.26nM)
JAK3inactive (10001nM)inactive (97.99%)inactive (>3981.07nM)
TYK2inactive (10001nM)inactive (99.85%)inactive (>1995.26nM)
TK - Met

Bioactivity
KinaseDRxRBCMetz
METinactive (10001nM)inactive (109.98%)inactive (>2511.89nM)
RONinactive (10001nM)inactive (84.73%)inactive (>3981.07nM)
TK - Musk

Bioactivity
KinaseDRxRBCMetz
MUSKinactive (10001nM)inactive (95.65%)-
TK - Ret

Bioactivity
KinaseDRxRBCMetz
RETinactive (10001nM)inactive (93.28%)inactive (>3162.28nM)
TK - Sev

Bioactivity
KinaseDRxRBCMetz
ROSinactive (10001nM)inactive (85.92%)inactive (>2511.89nM)
TK - Syk

Bioactivity
KinaseDRxRBCMetz
SYKinactive (10001nM)inactive (103.15%)inactive (>1584.89nM)
ZAP70inactive (10001nM)inactive (101.04%)-
TK - Tie

Bioactivity
KinaseDRxRBCMetz
TIE1inactive (10001nM)--
TIE2inactive (10001nM)inactive (98.39%)-
TK - Ack

Bioactivity
KinaseDRxRBCMetz
TNK1inactive (10001nM)--
ACKinactive (10001nM)inactive (94.37%)inactive (>3981.07nM)
TK - Trk

Bioactivity
KinaseDRxRBCMetz
TRKAinactive (10001nM)inactive (102.04%)inactive (>2511.89nM)
TRKBinactive (10001nM)inactive (95.81%)inactive (>3981.07nM)
TRKCinactive (10001nM)inactive (95.15%)inactive (>3162.28nM)

TKL


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
121051
541-
5231
10852
4322
4311
2111
TKL - STKR

Bioactivity
KinaseDRxRBCMetz
ALK2inactive (10001nM)inactive (100.78%)inactive (>3981.07nM)
ALK4inactive (10001nM)inactive (103.68%)-
ACTR2inactive (10001nM)--
ACTR2Binactive (10001nM)--
ALK1inactive (10001nM)inactive (105.65%)-
BMPR1Ainactive (10001nM)--
BMPR1Binactive (10001nM)--
BMPR2inactive (10001nM)--
TGFbR1inactive (10001nM)inactive (99.68%)-
TGFbR2inactive (10001nM)inactive (97.67%)-
TKL - RIPK

Bioactivity
KinaseDRxRBCMetz
SgK288inactive (10001nM)--
RIPK1inactive (10001nM)--
RIPK2inactive (10001nM)inactive (102.37%)-
ANKRD3inactive (10001nM)--
TKL - RAF

Bioactivity
KinaseDRxRBCMetz
BRAFinactive (10001nM)inactive (95.59%)-
RAF1active (1700nM)active (47.86%)-
ARAF-inactive (95.04%)-
TKL - MLK

Bioactivity
KinaseDRxRBCMetz
DLKinactive (10001nM)--
LZKinactive (10001nM)--
MLK1inactive (10001nM)inactive (102.29%)-
MLK2inactive (10001nM)inactive (105.28%)inactive (>3162.28nM)
MLK3inactive (10001nM)inactive (99.71%)-
TAK1inactive (10001nM)inactive (111.24%)-
HH498inactive (4300nM)--
ZAKactive (2600nM)inactive (98.2%)inactive (>7943.28nM)
TKL - IRAK

Bioactivity
KinaseDRxRBCMetz
IRAK1active (1200nM)inactive (99.75%)inactive (7943.28nM)
IRAK3inactive (10001nM)--
IRAK4inactive (10001nM)inactive (100.62%)inactive (>10000nM)
TKL - LISK

Bioactivity
KinaseDRxRBCMetz
LIMK1inactive (10001nM)inactive (90.09%)inactive (>2511.89nM)
LIMK2inactive (10001nM)--
TESK1inactive (10001nM)--
TKL - LRRK

Bioactivity
KinaseDRxRBCMetz
LRRK2inactive (10001nM)inactive (98.26%)inactive (>2511.89nM)

Atypical


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
52--
61--
33--
61-1
5-1-
Atypical - ABC1

Bioactivity
KinaseDRxRBCMetz
ADCK3inactive (10001nM)--
ADCK4inactive (10001nM)--
Atypical - PIKK

Bioactivity
KinaseDRxRBCMetz
FRAPinactive (10001nM)--
Atypical - RIO

Bioactivity
KinaseDRxRBCMetz
RIOK1inactive (10001nM)--
RIOK2inactive (10001nM)--
RIOK3inactive (10001nM)--
Atypical - Alpha

Bioactivity
KinaseDRxRBCMetz
ChaK2inactive (10001nM)--
eEF2K--inactive (>3981.07nM)
Atypical - PDHK

Bioactivity
KinaseDRxRBCMetz
PDHK1-inactive (95.24%)-

AGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
3333
7753
7361
441-
51--
1111
5332
3221
9595
2232
8184
3131
33--
AGC - Akt

Bioactivity
KinaseDRxRBCMetz
AKT1inactive (10001nM)inactive (93.14%)inactive (>7943.28nM)
AKT2inactive (10001nM)inactive (111.81%)inactive (>7943.28nM)
AKT3inactive (10001nM)inactive (92.41%)inactive (>10000nM)
AGC - DMPK

Bioactivity
KinaseDRxRBCMetz
CRIKinactive (10001nM)--
DMPK1inactive (10001nM)inactive (98.15%)-
DMPK2inactive (10001nM)--
MRCKainactive (10001nM)inactive (86.68%)inactive (>10000nM)
MRCKbinactive (10001nM)inactive (97.1%)-
ROCK1inactive (10001nM)inactive (100.46%)inactive (>5011.87nM)
ROCK2inactive (10001nM)inactive (102.72%)inactive (>6309.57nM)
AGC - GRK

Bioactivity
KinaseDRxRBCMetz
RHOKinactive (10001nM)--
GPRK4inactive (10001nM)inactive (104.83%)-
GPRK7inactive (10001nM)inactive (99.57%)-
BARK1-inactive (112.14%)-
BARK2-inactive (96.78%)-
GPRK5-inactive (95.02%)inactive (>3981.07nM)
GPRK6-inactive (102.62%)-
AGC - NDR

Bioactivity
KinaseDRxRBCMetz
LATS1inactive (10001nM)--
LATS2inactive (10001nM)--
NDR1inactive (10001nM)inactive (100.39%)-
NDR2inactive (10001nM)--
AGC - MAST

Bioactivity
KinaseDRxRBCMetz
MAST1inactive (10001nM)--
AGC - PDK1

Bioactivity
KinaseDRxRBCMetz
PDK1inactive (10001nM)inactive (95.24%)inactive (>3981.07nM)
AGC - PKA

Bioactivity
KinaseDRxRBCMetz
PKACainactive (10001nM)inactive (95.37%)inactive (>3162.28nM)
PKACbinactive (10001nM)--
PRKXinactive (10001nM)inactive (102.97%)inactive (>2511.89nM)
PKACg-inactive (106.18%)-
AGC - PKN

Bioactivity
KinaseDRxRBCMetz
PKN1inactive (10001nM)inactive (98.94%)-
PKN2inactive (10001nM)inactive (96.95%)inactive (>7943.28nM)
AGC - PKC

Bioactivity
KinaseDRxRBCMetz
PKCdinactive (10001nM)inactive (104.89%)inactive (>7943.28nM)
PKCeinactive (10001nM)inactive (97.24%)-
PKChinactive (10001nM)inactive (110.82%)-
PKCiinactive (10001nM)inactive (91.16%)inactive (>5011.87nM)
PKCtinactive (10001nM)inactive (100.57%)inactive (>2511.89nM)
PKCa-inactive (98.24%)-
PKCg-inactive (91.61%)inactive (>7943.28nM)
PKCz-inactive (96.25%)inactive (>7943.28nM)
PKCb-inactive (101.9%)-
AGC - PKG

Bioactivity
KinaseDRxRBCMetz
PKG1inactive (10001nM)inactive (86%)inactive (>1995.26nM)
PKG2inactive (10001nM)inactive (95.72%)inactive (>1584.89nM)
AGC - RSK

Bioactivity
KinaseDRxRBCMetz
p70S6Kinactive (10001nM)inactive (94.78%)inactive (>6309.57nM)
MSK1-inactive (98.33%)inactive (>1995.26nM)
MSK2-inactive (103.24%)inactive (>1584.89nM)
p70S6Kb-inactive (102.82%)-
RSK2-inactive (100.67%)inactive (>5011.87nM)
RSK4-inactive (101.1%)-
RSK1-inactive (100.54%)-
RSK3-inactive (97.95%)-
AGC - SGK

Bioactivity
KinaseDRxRBCMetz
SGK3inactive (10001nM)inactive (103.68%)-
SGK1-inactive (110.04%)inactive (>7943.28nM)
SGK2---
AGC - YANK

Bioactivity
KinaseDRxRBCMetz
YANK1inactive (10001nM)--
YANK2inactive (10001nM)--
YANK3inactive (10001nM)--

CAMK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
2019139
5452
4444
11--
1111
5542
3311
5454
542-
2221
3333
3332
11-1
5122
CAMK - CAMKL

Bioactivity
KinaseDRxRBCMetz
AMPKa1inactive (10001nM)-inactive (>3981.07nM)
AMPKa2inactive (10001nM)--
NuaK1inactive (10001nM)inactive (98.84%)-
BRSK1inactive (10001nM)inactive (98.25%)inactive (>10000nM)
BRSK2inactive (10001nM)inactive (102.48%)-
CHK1inactive (10001nM)inactive (109.49%)inactive (>6309.57nM)
HUNKinactive (10001nM)--
LKB1inactive (10001nM)inactive (103.62%)-
MARK1inactive (10001nM)inactive (74.77%)-
MARK2inactive (10001nM)inactive (94.71%)inactive (>7943.28nM)
MARK3inactive (10001nM)inactive (94.14%)inactive (>6309.57nM)
MARK4inactive (10001nM)inactive (102.3%)inactive (>5011.87nM)
MELKactive (1900nM)inactive (89.16%)inactive (>1258.93nM)
NIM1inactive (10001nM)--
QSKinactive (10001nM)--
SIKinactive (10001nM)--
QIKinactive (10001nM)inactive (100.06%)inactive (>3981.07nM)
NuaK2inactive (10001nM)inactive (98.55%)-
SNRKinactive (10001nM)--
PASK-inactive (98.86%)-
CAMK - CAMK1

Bioactivity
KinaseDRxRBCMetz
CaMK1ainactive (10001nM)inactive (102.44%)inactive (>6309.57nM)
CaMK1dinactive (10001nM)inactive (95.01%)inactive (>2511.89nM)
CaMK1ginactive (10001nM)inactive (98.43%)-
CaMK4inactive (10001nM)inactive (101.93%)-
CaMK1b-inactive (100.79%)-
CAMK - CAMK2

Bioactivity
KinaseDRxRBCMetz
CaMK2ainactive (10001nM)inactive (100.14%)inactive (>6309.57nM)
CaMK2binactive (10001nM)inactive (97.56%)inactive (>7943.28nM)
CaMK2dinactive (10001nM)inactive (97.38%)inactive (>6309.57nM)
CaMK2ginactive (10001nM)inactive (102.06%)inactive (>6309.57nM)
CAMK - CASK

Bioactivity
KinaseDRxRBCMetz
CASKinactive (10001nM)--
CAMK - RAD53

Bioactivity
KinaseDRxRBCMetz
CHK2inactive (10001nM)inactive (99.06%)inactive (>5011.87nM)
CAMK - DAPK

Bioactivity
KinaseDRxRBCMetz
DAPK1inactive (10001nM)inactive (104.46%)-
DAPK2inactive (10001nM)inactive (98.51%)-
DAPK3inactive (10001nM)inactive (91.51%)inactive (>3981.07nM)
DRAK1inactive (5300nM)inactive (92.39%)inactive (>3981.07nM)
DRAK2inactive (10001nM)--
CAMK - DCAMKL

Bioactivity
KinaseDRxRBCMetz
DCLK1inactive (10001nM)-inactive (>10000nM)
DCLK2inactive (10001nM)inactive (102.02%)-
DCLK3inactive (10001nM)--
CAMK - MAPKAPK

Bioactivity
KinaseDRxRBCMetz
MAPKAPK2inactive (10001nM)inactive (97.92%)inactive (>7943.28nM)
MAPKAPK5inactive (10001nM)inactive (90.82%)inactive (>1584.89nM)
MNK1inactive (10001nM)inactive (94.58%)-
MNK2inactive (10001nM)inactive (106.3%)inactive (>10000nM)
MAPKAPK3-inactive (97.76%)inactive (>10000nM)
CAMK - MLCK

Bioactivity
KinaseDRxRBCMetz
caMLCKinactive (10001nM)--
smMLCKinactive (10001nM)inactive (92.62%)-
skMLCKinactive (10001nM)inactive (101.69%)-
SgK085inactive (10001nM)--
CAMK - PHK

Bioactivity
KinaseDRxRBCMetz
PHKg1inactive (10001nM)inactive (93.42%)-
PHKg2inactive (10001nM)inactive (92.94%)inactive (>5011.87nM)
CAMK - PIM

Bioactivity
KinaseDRxRBCMetz
PIM1inactive (10001nM)inactive (94.42%)inactive (>6309.57nM)
PIM2inactive (10001nM)inactive (98.42%)inactive (>1584.89nM)
PIM3inactive (10001nM)inactive (95.65%)inactive (>7943.28nM)
CAMK - PKD

Bioactivity
KinaseDRxRBCMetz
PKD1inactive (10001nM)inactive (97.93%)-
PKD2inactive (10001nM)inactive (95.11%)inactive (>10000nM)
PKD3inactive (10001nM)inactive (91.29%)inactive (>5011.87nM)
CAMK - STK33

Bioactivity
KinaseDRxRBCMetz
STK33inactive (10001nM)inactive (91.48%)-
CAMK - TSSK

Bioactivity
KinaseDRxRBCMetz
TSSK1inactive (10001nM)inactive (97.03%)inactive (>1584.89nM)
TSSK2-inactive (100.47%)inactive (>1584.89nM)

STE


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
883-
3127239
7732
2-2-
STE - STE11

Bioactivity
KinaseDRxRBCMetz
MAP3K5inactive (10001nM)inactive (100.55%)-
MAP3K6inactive (10001nM)--
MAP3K1inactive (10001nM)--
MAP3K7inactive (10001nM)--
MAP3K2inactive (10001nM)inactive (110.13%)-
MAP3K3inactive (10001nM)inactive (105.91%)-
MAP3K4inactive (10001nM)--
MAP3K8inactive (10001nM)--
STE - STE20

Bioactivity
KinaseDRxRBCMetz
HPK1inactive (10001nM)--
LOKinactive (10001nM)inactive (102.72%)-
GCKinactive (10001nM)inactive (106.71%)inactive (>3981.07nM)
KHS2inactive (10001nM)--
HGKinactive (10001nM)inactive (99.77%)inactive (>5011.87nM)
KHS1inactive (10001nM)inactive (102.11%)inactive (>7943.28nM)
MINKinactive (10001nM)inactive (98.48%)inactive (>7943.28nM)
MST1inactive (10001nM)inactive (101.42%)-
MST2inactive (10001nM)inactive (97.89%)inactive (>6309.57nM)
MST3inactive (10001nM)inactive (107.06%)-
MST4inactive (10001nM)inactive (103.02%)-
MYO3Ainactive (10001nM)--
MYO3Binactive (10001nM)inactive (85.66%)-
OSR1inactive (10001nM)inactive (100.88%)-
PAK1inactive (10001nM)inactive (105.32%)inactive (>10000nM)
PAK2inactive (10001nM)inactive (102.29%)-
PAK3inactive (10001nM)inactive (106.05%)-
PAK4inactive (10001nM)inactive (91.5%)inactive (>5011.87nM)
PAK6inactive (10001nM)inactive (111.87%)-
PAK5inactive (10001nM)inactive (97.03%)-
SLKinactive (10001nM)inactive (103.78%)inactive (>10000nM)
STLK3inactive (10001nM)inactive (93.24%)-
TAO1inactive (10001nM)inactive (101.24%)inactive (3981.07nM)
TAO2inactive (10001nM)inactive (103.68%)-
TAO3inactive (10001nM)inactive (94.7%)-
TNIKinactive (10001nM)--
YSK1inactive (10001nM)inactive (98.38%)-
STE - STE7

Bioactivity
KinaseDRxRBCMetz
MAP2K1inactive (10001nM)inactive (103.73%)inactive (>3162.28nM)
MAP2K2inactive (10001nM)inactive (96.61%)inactive (>3981.07nM)
MAP2K3inactive (10001nM)--
MAP2K4inactive (10001nM)--
MAP2K5inactive (10001nM)--
MAP2K6inactive (10001nM)inactive (96.3%)-
MAP2K7inactive (10001nM)--
STE - STE-Unique

Bioactivity
KinaseDRxRBCMetz
COT-inactive (92.65%)-
NIK-inactive (99.13%)-

CMGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
208-7
54--
4442
3221
10896
1414108
2222
32--
3331
CMGC - CDK

Bioactivity
KinaseDRxRBCMetz
PITSLREinactive (10001nM)--
CHEDinactive (10001nM)--
CDK11inactive (5500nM)--
PCTAIRE1inactive (10001nM)--
PCTAIRE2inactive (10001nM)--
PCTAIRE3inactive (10001nM)--
PFTAIRE2inactive (10001nM)--
PFTAIRE1inactive (10001nM)--
CDC2--inactive (>7943.28nM)
CDK2--inactive (>7943.28nM)
CDK5--inactive (>6309.57nM)
CDK8--inactive (>3981.07nM)
CDK7--inactive (>3981.07nM)
CDK9--inactive (>1584.89nM)
CMGC - CDKL

Bioactivity
KinaseDRxRBCMetz
CDKL1inactive (10001nM)--
CDKL2inactive (10001nM)--
CDKL3inactive (10001nM)--
CDKL5inactive (10001nM)--
CMGC - CLK

Bioactivity
KinaseDRxRBCMetz
CLK1inactive (4500nM)inactive (98.64%)-
CLK2inactive (10001nM)inactive (90.37%)inactive (>5011.87nM)
CLK3inactive (10001nM)inactive (96.76%)-
CLK4active (2100nM)inactive (93.98%)inactive (1258.93nM)
CMGC - CK2

Bioactivity
KinaseDRxRBCMetz
CK2a1inactive (10001nM)inactive (106.94%)inactive (>3981.07nM)
CK2a2inactive (10001nM)inactive (94.51%)-
CMGC - DYRK

Bioactivity
KinaseDRxRBCMetz
DYRK1Ainactive (10001nM)inactive (103.48%)inactive (>3162.28nM)
DYRK1Binactive (10001nM)inactive (97.87%)inactive (>2511.89nM)
DYRK2inactive (10001nM)inactive (99.17%)-
HIPK1inactive (10001nM)inactive (97%)-
HIPK2inactive (10001nM)inactive (104.35%)inactive (>3162.28nM)
HIPK3inactive (10001nM)inactive (98.87%)-
HIPK4active (960nM)inactive (99.51%)inactive (>7943.28nM)
PRP4inactive (10001nM)--
DYRK3-inactive (96.37%)inactive (>6309.57nM)
DYRK4-inactive (103.53%)inactive (>7943.28nM)
CMGC - MAPK

Bioactivity
KinaseDRxRBCMetz
Erk1inactive (10001nM)inactive (101.53%)-
Erk2inactive (10001nM)inactive (89.92%)inactive (>7943.28nM)
Erk3inactive (10001nM)--
Erk4inactive (10001nM)--
Erk5inactive (10001nM)--
Erk7inactive (10001nM)--
JNK1inactive (5000nM)inactive (93.89%)inactive (>2511.89nM)
JNK2inactive (10001nM)inactive (95.22%)inactive (>3981.07nM)
JNK3inactive (3100nM)inactive (90.8%)active (1000nM)
NLKinactive (10001nM)inactive (103.65%)-
p38ainactive (10001nM)inactive (98.75%)inactive (>3981.07nM)
p38binactive (10001nM)inactive (97.98%)-
p38dinactive (10001nM)inactive (97.16%)inactive (>7943.28nM)
p38ginactive (10001nM)inactive (93.05%)inactive (>6309.57nM)
CMGC - GSK

Bioactivity
KinaseDRxRBCMetz
GSK3Ainactive (10001nM)inactive (99.98%)inactive (>6309.57nM)
GSK3Binactive (10001nM)inactive (99.02%)inactive (>5011.87nM)
CMGC - RCK

Bioactivity
KinaseDRxRBCMetz
ICKinactive (10001nM)--
MAKinactive (10001nM)--
CMGC - SRPK

Bioactivity
KinaseDRxRBCMetz
SRPK1inactive (10001nM)inactive (99.52%)inactive (>7943.28nM)
SRPK2inactive (10001nM)inactive (104.27%)-
MSSK1inactive (10001nM)inactive (97.97%)-

CK1


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBCMetz
7765
311-
CK1 - CK1

Bioactivity
KinaseDRxRBCMetz
CK1ainactive (10001nM)inactive (102.22%)inactive (>5011.87nM)
CK1a2inactive (10001nM)--
CK1dinactive (10001nM)inactive (97.99%)inactive (>7943.28nM)
CK1einactive (10001nM)inactive (92.42%)-
CK1g1inactive (10001nM)inactive (101.3%)inactive (>6309.57nM)
CK1g2inactive (10001nM)inactive (96.58%)inactive (>7943.28nM)
CK1g3inactive (10001nM)inactive (100.3%)inactive (>6309.57nM)
CK1 - VRK

Bioactivity
KinaseDRxRBCMetz
VRK2inactive (10001nM)--
VRK1-inactive (96.66%)-