Compound Information


Test on : DRx, RBC

Compound Name
DRx, RBC : Nilotinib

Inchikey
Same : HHZIURLSWUIHRB-N
DRx, RBC : HHZIURLSWUIHRB-UHFFFAOYSA-N

ChemSpider
DRx, RBC : 559260

Pubchem CID
DRx, RBC : 644241

ChEMBL
DRx, RBC : CHEMBL255863




DRx RBC Metz Millipore GPCR
bioactivity Kd (nM) Remain Activity (%) Ki (nM) Remain Activity (%) Inhibition (%)
active criteria <3000nM <50% <1000nM <50% >50%

Other


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
441
333
222
42-
21-
444
1198
331
443
111
32-
21-
543
221
111
1-1
1-1
4-2
Other - NAK

Bioactivity
KinaseDRxRBC
AAK1inactive (10001nM)-
BIKEinactive (10001nM)-
GAKinactive (10001nM)-
MPSK1inactive (10001nM)inactive (93.43%)
Other - Aur

Bioactivity
KinaseDRxRBC
AurAinactive (10001nM)inactive (78.92%)
AurBinactive (10001nM)inactive (103.66%)
AurCinactive (10001nM)inactive (87.18%)
Other - CAMKK

Bioactivity
KinaseDRxRBC
CaMKK1inactive (10001nM)inactive (91.1%)
CaMKK2inactive (10001nM)inactive (97.52%)
Other - PEK

Bioactivity
KinaseDRxRBC
HRIinactive (10001nM)-
PKRinactive (10001nM)-
Other - IRE

Bioactivity
KinaseDRxRBC
IRE1inactive (10001nM)-
Other - IKK

Bioactivity
KinaseDRxRBC
IKKainactive (10001nM)inactive (98.73%)
IKKbinactive (10001nM)inactive (82.83%)
IKKeinactive (10001nM)inactive (94.6%)
TBK1inactive (10001nM)inactive (103.14%)
Other - NEK

Bioactivity
KinaseDRxRBC
NEK1inactive (10001nM)inactive (74.97%)
NEK11inactive (10001nM)inactive (110.5%)
NEK2inactive (10001nM)inactive (103.39%)
NEK3inactive (10001nM)inactive (95.86%)
NEK4inactive (10001nM)inactive (101.86%)
NEK5inactive (10001nM)-
NEK6inactive (10001nM)inactive (93.57%)
NEK7inactive (10001nM)inactive (95.48%)
NEK9inactive (10001nM)inactive (98.53%)
Other - WEE

Bioactivity
KinaseDRxRBC
MYT1inactive (10001nM)-
Wee1inactive (10001nM)inactive (99.02%)
Wee1Binactive (10001nM)-
Other - PLK

Bioactivity
KinaseDRxRBC
PLK1inactive (10001nM)inactive (97.02%)
PLK2inactive (10001nM)inactive (107.37%)
PLK3inactive (10001nM)inactive (105.03%)
PLK4inactive (10001nM)-
Other - SgK496

Bioactivity
KinaseDRxRBC
SgK496inactive (10001nM)inactive (106.74%)
Other - NKF1

Bioactivity
KinaseDRxRBC
SBKinactive (10001nM)-
SgK110inactive (10001nM)-
Other - NKF4

Bioactivity
KinaseDRxRBC
CLIK1inactive (10001nM)-
Other - ULK

Bioactivity
KinaseDRxRBC
Fusedinactive (10001nM)-
ULK1inactive (10001nM)inactive (100.59%)
ULK2inactive (10001nM)inactive (104.22%)
ULK3inactive (10001nM)inactive (108.33%)
Other - TLK

Bioactivity
KinaseDRxRBC
TLK1inactive (10001nM)-
TLK2inactive (10001nM)inactive (87.82%)
Other - TTK

Bioactivity
KinaseDRxRBC
TTKinactive (10001nM)inactive (97.9%)
Other - Haspin

Bioactivity
KinaseDRxRBC
Haspin-inactive (66.51%)
Other - TOPK

Bioactivity
KinaseDRxRBC
PBK-inactive (103.11%)
Other - WNK

Bioactivity
KinaseDRxRBC
Wnk2-inactive (102.24%)
Wnk3-inactive (100.36%)

TK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
222
222
333
111111
555
555
222
221
443
141312
222
222
444
333
333
444
222
111
111
111
222
221
221
333
TK - Abl

Bioactivity
KinaseDRxRBC
ABL1active (10nM)active (3.54%)
ABL2active (26nM)active (4.86%)
TK - ALK

Bioactivity
KinaseDRxRBC
ALKinactive (10001nM)inactive (102.53%)
LTKinactive (10001nM)inactive (100.63%)
TK - Axl

Bioactivity
KinaseDRxRBC
AXLinactive (10001nM)inactive (64.77%)
MERinactive (10001nM)inactive (96.37%)
TYRO3inactive (10001nM)inactive (96.46%)
TK - Src

Bioactivity
KinaseDRxRBC
BLKactive (500nM)inactive (87.58%)
BRKinactive (10001nM)inactive (70.41%)
FGRactive (320nM)inactive (63.71%)
FRKactive (86nM)active (16.19%)
FYNactive (1600nM)inactive (101.51%)
HCKactive (390nM)active (46.65%)
LCKactive (47nM)active (22.22%)
LYNactive (100nM)inactive (52.91%)
SRCactive (1900nM)inactive (95.19%)
SRMinactive (10001nM)inactive (118.47%)
YESactive (1100nM)inactive (66.12%)
TK - Tec

Bioactivity
KinaseDRxRBC
BMXinactive (10001nM)inactive (99.83%)
BTKinactive (10001nM)inactive (100.62%)
ITKinactive (10001nM)inactive (101.94%)
TECinactive (10001nM)inactive (88.25%)
TXKinactive (10001nM)inactive (103.61%)
TK - PDGFR

Bioactivity
KinaseDRxRBC
FMSactive (45nM)active (17.53%)
FLT3inactive (10001nM)inactive (77.39%)
KITactive (29nM)inactive (55.17%)
PDGFRaactive (180nM)active (18.08%)
PDGFRbactive (73nM)active (28.39%)
TK - Csk

Bioactivity
KinaseDRxRBC
CSKactive (2400nM)active (42.42%)
CTKinactive (10001nM)inactive (79.21%)
TK - DDR

Bioactivity
KinaseDRxRBC
DDR1active (1.1nM)-
DDR2active (33nM)active (1.77%)
TK - EGFR

Bioactivity
KinaseDRxRBC
EGFRinactive (10001nM)inactive (86.91%)
ErbB2inactive (10001nM)inactive (103.79%)
ErbB3inactive (10001nM)-
ErbB4inactive (10001nM)inactive (82.08%)
TK - Eph

Bioactivity
KinaseDRxRBC
EphA1active (590nM)inactive (63.22%)
EphA2active (230nM)active (10.82%)
EphA3active (110nM)active (40.82%)
EphA4active (330nM)active (12.03%)
EphA5active (1900nM)active (22.56%)
EphA6active (640nM)active (46.95%)
EphA7inactive (10001nM)inactive (86.38%)
EphA8active (37nM)active (28.4%)
EphB1active (1300nM)active (10.56%)
EphB2active (640nM)active (1.55%)
EphB3active (1000nM)active (5.59%)
EphB4active (730nM)active (11.44%)
EphB6active (500nM)-
TK - FAK

Bioactivity
KinaseDRxRBC
FAKinactive (10001nM)inactive (106.84%)
PYK2inactive (10001nM)inactive (94.55%)
TK - Fer

Bioactivity
KinaseDRxRBC
FERinactive (10001nM)inactive (93.63%)
FESinactive (10001nM)inactive (95.91%)
TK - FGFR

Bioactivity
KinaseDRxRBC
FGFR1inactive (10001nM)inactive (99.59%)
FGFR2inactive (10001nM)inactive (96.54%)
FGFR3inactive (10001nM)inactive (103.1%)
FGFR4inactive (10001nM)inactive (99.35%)
TK - VEGFR

Bioactivity
KinaseDRxRBC
FLT1inactive (10001nM)inactive (99.22%)
FLT4inactive (10001nM)inactive (91.72%)
KDRinactive (10001nM)inactive (91.99%)
TK - InsR

Bioactivity
KinaseDRxRBC
IGF1Rinactive (10001nM)inactive (88.44%)
INSRinactive (10001nM)inactive (102.32%)
IRRinactive (10001nM)inactive (122.75%)
TK - JakA

Bioactivity
KinaseDRxRBC
JAK1inactive (10001nM)inactive (103.82%)
JAK2inactive (10001nM)inactive (100.43%)
JAK3inactive (10001nM)inactive (94.24%)
TYK2inactive (10001nM)inactive (99.29%)
TK - Met

Bioactivity
KinaseDRxRBC
METinactive (10001nM)inactive (95.77%)
RONinactive (10001nM)inactive (94.02%)
TK - Musk

Bioactivity
KinaseDRxRBC
MUSKinactive (10001nM)inactive (91.15%)
TK - Ret

Bioactivity
KinaseDRxRBC
RETactive (870nM)inactive (70.51%)
TK - Sev

Bioactivity
KinaseDRxRBC
ROSinactive (10001nM)inactive (99.37%)
TK - Syk

Bioactivity
KinaseDRxRBC
SYKinactive (10001nM)inactive (109.58%)
ZAP70inactive (10001nM)inactive (95.07%)
TK - Tie

Bioactivity
KinaseDRxRBC
TIE1active (1000nM)-
TIE2active (1000nM)inactive (101.82%)
TK - Ack

Bioactivity
KinaseDRxRBC
TNK1inactive (10001nM)-
ACKinactive (10001nM)inactive (82.57%)
TK - Trk

Bioactivity
KinaseDRxRBC
TRKAinactive (10001nM)inactive (91.42%)
TRKBactive (490nM)inactive (85.41%)
TRKCactive (600nM)inactive (67.69%)

TKL


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
12105
541
523
1085
432
431
211
TKL - STKR

Bioactivity
KinaseDRxRBC
ALK2inactive (10001nM)inactive (111.84%)
ALK4inactive (10001nM)inactive (102.9%)
ACTR2inactive (10001nM)-
ACTR2Binactive (10001nM)-
ALK1inactive (10001nM)inactive (116.46%)
BMPR1Ainactive (10001nM)-
BMPR1Binactive (10001nM)-
BMPR2inactive (10001nM)-
TGFbR1inactive (10001nM)inactive (99.92%)
TGFbR2inactive (10001nM)inactive (100.23%)
TKL - RIPK

Bioactivity
KinaseDRxRBC
SgK288inactive (10001nM)-
RIPK1inactive (10001nM)-
RIPK2inactive (10001nM)inactive (110.32%)
ANKRD3inactive (10001nM)-
TKL - RAF

Bioactivity
KinaseDRxRBC
BRAFactive (1700nM)active (11.5%)
RAF1inactive (3900nM)-
ARAF-inactive (77.26%)
TKL - MLK

Bioactivity
KinaseDRxRBC
DLKinactive (10001nM)-
LZKinactive (10001nM)-
MLK1inactive (10001nM)inactive (112.08%)
MLK2inactive (10001nM)inactive (110.26%)
MLK3inactive (10001nM)inactive (109.02%)
TAK1inactive (10001nM)inactive (89.16%)
HH498active (360nM)-
ZAKactive (11nM)active (17.76%)
TKL - IRAK

Bioactivity
KinaseDRxRBC
IRAK1inactive (10001nM)inactive (93.29%)
IRAK3inactive (10001nM)-
IRAK4inactive (10001nM)inactive (80.18%)
TKL - LISK

Bioactivity
KinaseDRxRBC
LIMK1inactive (10001nM)inactive (94%)
LIMK2inactive (10001nM)-
TESK1inactive (10001nM)-
TKL - LRRK

Bioactivity
KinaseDRxRBC
LRRK2inactive (10001nM)inactive (81.08%)

Atypical


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
52-
61-
33-
61-
5-1
Atypical - ABC1

Bioactivity
KinaseDRxRBC
ADCK3inactive (10001nM)-
ADCK4inactive (10001nM)-
Atypical - PIKK

Bioactivity
KinaseDRxRBC
FRAPinactive (10001nM)-
Atypical - RIO

Bioactivity
KinaseDRxRBC
RIOK1inactive (10001nM)-
RIOK2inactive (10001nM)-
RIOK3inactive (10001nM)-
Atypical - Alpha

Bioactivity
KinaseDRxRBC
ChaK2inactive (10001nM)-
Atypical - PDHK

Bioactivity
KinaseDRxRBC
PDHK1-inactive (84.63%)

AGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
333
775
736
441
51-
111
533
322
959
223
818
313
33-
AGC - Akt

Bioactivity
KinaseDRxRBC
AKT1inactive (10001nM)inactive (99.67%)
AKT2inactive (10001nM)inactive (102.52%)
AKT3inactive (10001nM)inactive (74.76%)
AGC - DMPK

Bioactivity
KinaseDRxRBC
CRIKinactive (10001nM)-
DMPK1inactive (10001nM)inactive (98.11%)
DMPK2inactive (10001nM)-
MRCKainactive (10001nM)inactive (88.53%)
MRCKbactive (910nM)inactive (99.6%)
ROCK1inactive (10001nM)inactive (110.07%)
ROCK2inactive (10001nM)inactive (97.1%)
AGC - GRK

Bioactivity
KinaseDRxRBC
RHOKinactive (10001nM)-
GPRK4inactive (10001nM)inactive (89.22%)
GPRK7inactive (10001nM)inactive (99.81%)
BARK1-inactive (95.77%)
BARK2-inactive (95.08%)
GPRK5-inactive (98.64%)
GPRK6-inactive (107.84%)
AGC - NDR

Bioactivity
KinaseDRxRBC
LATS1inactive (10001nM)-
LATS2inactive (10001nM)-
NDR1inactive (10001nM)inactive (98.05%)
NDR2inactive (10001nM)-
AGC - MAST

Bioactivity
KinaseDRxRBC
MAST1inactive (10001nM)-
AGC - PDK1

Bioactivity
KinaseDRxRBC
PDK1inactive (10001nM)inactive (84.63%)
AGC - PKA

Bioactivity
KinaseDRxRBC
PKACainactive (10001nM)inactive (98.63%)
PKACbinactive (10001nM)-
PRKXinactive (10001nM)inactive (109.33%)
PKACg-inactive (112.55%)
AGC - PKN

Bioactivity
KinaseDRxRBC
PKN1inactive (10001nM)inactive (101.88%)
PKN2inactive (10001nM)inactive (95.96%)
AGC - PKC

Bioactivity
KinaseDRxRBC
PKCdinactive (10001nM)inactive (100.15%)
PKCeinactive (10001nM)inactive (96.94%)
PKChinactive (10001nM)inactive (121.21%)
PKCiinactive (10001nM)inactive (108.45%)
PKCtinactive (10001nM)inactive (75.38%)
PKCa-inactive (83.54%)
PKCg-inactive (81.68%)
PKCz-inactive (87.02%)
PKCb-inactive (96.3%)
AGC - PKG

Bioactivity
KinaseDRxRBC
PKG1inactive (10001nM)inactive (90.31%)
PKG2inactive (10001nM)inactive (108.81%)
AGC - RSK

Bioactivity
KinaseDRxRBC
p70S6Kinactive (10001nM)inactive (97.97%)
MSK1-inactive (95.64%)
MSK2-inactive (102.58%)
p70S6Kb-inactive (100.03%)
RSK2-inactive (104.13%)
RSK4-inactive (98.95%)
RSK1-inactive (103.68%)
RSK3-inactive (97.15%)
AGC - SGK

Bioactivity
KinaseDRxRBC
SGK3inactive (10001nM)inactive (102.1%)
SGK1-inactive (124.61%)
SGK2-inactive (103.33%)
AGC - YANK

Bioactivity
KinaseDRxRBC
YANK1inactive (10001nM)-
YANK2inactive (10001nM)-
YANK3inactive (10001nM)-

CAMK


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
201913
545
444
11-
111
554
331
545
542
222
333
333
11-
512
CAMK - CAMKL

Bioactivity
KinaseDRxRBC
AMPKa1inactive (10001nM)-
AMPKa2inactive (10001nM)-
NuaK1inactive (10001nM)inactive (107.66%)
BRSK1inactive (10001nM)inactive (97.97%)
BRSK2inactive (10001nM)inactive (101.47%)
CHK1inactive (10001nM)inactive (90.91%)
HUNKinactive (10001nM)-
LKB1inactive (10001nM)inactive (109.43%)
MARK1inactive (10001nM)inactive (147.7%)
MARK2inactive (10001nM)inactive (141.93%)
MARK3inactive (10001nM)inactive (93.83%)
MARK4inactive (10001nM)inactive (102.4%)
MELKinactive (10001nM)inactive (90.03%)
NIM1inactive (10001nM)-
QSKinactive (10001nM)-
SIKinactive (10001nM)-
QIKinactive (10001nM)inactive (102.92%)
NuaK2inactive (10001nM)inactive (100.81%)
SNRKinactive (10001nM)-
PASK-inactive (102.03%)
CAMK - CAMK1

Bioactivity
KinaseDRxRBC
CaMK1ainactive (10001nM)inactive (104.5%)
CaMK1dinactive (10001nM)inactive (87.65%)
CaMK1ginactive (10001nM)inactive (109.56%)
CaMK4inactive (10001nM)inactive (101.5%)
CaMK1b-inactive (100.68%)
CAMK - CAMK2

Bioactivity
KinaseDRxRBC
CaMK2ainactive (10001nM)inactive (96.09%)
CaMK2binactive (10001nM)inactive (94.97%)
CaMK2dinactive (10001nM)inactive (90.05%)
CaMK2ginactive (10001nM)inactive (111.06%)
CAMK - CASK

Bioactivity
KinaseDRxRBC
CASKinactive (10001nM)-
CAMK - RAD53

Bioactivity
KinaseDRxRBC
CHK2inactive (10001nM)inactive (101.61%)
CAMK - DAPK

Bioactivity
KinaseDRxRBC
DAPK1inactive (10001nM)inactive (101.89%)
DAPK2inactive (10001nM)inactive (100.49%)
DAPK3inactive (10001nM)inactive (96.96%)
DRAK1inactive (10001nM)inactive (98.93%)
DRAK2inactive (10001nM)-
CAMK - DCAMKL

Bioactivity
KinaseDRxRBC
DCLK1inactive (10001nM)-
DCLK2inactive (10001nM)inactive (101.74%)
DCLK3inactive (10001nM)-
CAMK - MAPKAPK

Bioactivity
KinaseDRxRBC
MAPKAPK2inactive (10001nM)inactive (94.21%)
MAPKAPK5inactive (10001nM)inactive (91.52%)
MNK1inactive (10001nM)inactive (101.55%)
MNK2inactive (10001nM)inactive (103.06%)
MAPKAPK3-inactive (101.69%)
CAMK - MLCK

Bioactivity
KinaseDRxRBC
caMLCKinactive (10001nM)-
smMLCKinactive (10001nM)inactive (93.28%)
skMLCKinactive (10001nM)inactive (110.96%)
SgK085inactive (10001nM)-
CAMK - PHK

Bioactivity
KinaseDRxRBC
PHKg1inactive (10001nM)inactive (91.03%)
PHKg2inactive (10001nM)inactive (97.89%)
CAMK - PIM

Bioactivity
KinaseDRxRBC
PIM1inactive (10001nM)inactive (97.41%)
PIM2inactive (10001nM)inactive (98.13%)
PIM3inactive (10001nM)inactive (97.77%)
CAMK - PKD

Bioactivity
KinaseDRxRBC
PKD1inactive (10001nM)inactive (99.73%)
PKD2inactive (10001nM)inactive (88.68%)
PKD3inactive (10001nM)inactive (89.42%)
CAMK - STK33

Bioactivity
KinaseDRxRBC
STK33inactive (10001nM)inactive (87.14%)
CAMK - TSSK

Bioactivity
KinaseDRxRBC
TSSK1inactive (10001nM)inactive (77.65%)
TSSK2-inactive (73.5%)

STE


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
883
312723
773
2-2
STE - STE11

Bioactivity
KinaseDRxRBC
MAP3K5inactive (10001nM)inactive (104.9%)
MAP3K6inactive (10001nM)-
MAP3K1inactive (10001nM)-
MAP3K7inactive (10001nM)-
MAP3K2inactive (10001nM)inactive (123.55%)
MAP3K3inactive (10001nM)inactive (115.13%)
MAP3K4inactive (10001nM)-
MAP3K8inactive (10001nM)-
STE - STE20

Bioactivity
KinaseDRxRBC
HPK1active (890nM)-
LOKinactive (6800nM)inactive (102.8%)
GCKinactive (10001nM)inactive (102.52%)
KHS2inactive (10001nM)-
HGKinactive (10001nM)inactive (105.67%)
KHS1inactive (10001nM)inactive (100.19%)
MINKinactive (10001nM)inactive (112.82%)
MST1inactive (10001nM)inactive (100.44%)
MST2inactive (10001nM)inactive (93.86%)
MST3inactive (10001nM)inactive (103.55%)
MST4inactive (10001nM)inactive (111.04%)
MYO3Ainactive (10001nM)-
MYO3Binactive (10001nM)inactive (85.05%)
OSR1inactive (10001nM)inactive (105.04%)
PAK1inactive (10001nM)inactive (117.03%)
PAK2inactive (10001nM)inactive (94.15%)
PAK3inactive (10001nM)inactive (108.24%)
PAK4inactive (10001nM)inactive (88.95%)
PAK6inactive (10001nM)inactive (107.26%)
PAK5inactive (10001nM)inactive (97.7%)
SLKinactive (10001nM)inactive (101.54%)
STLK3inactive (10001nM)inactive (96.33%)
TAO1inactive (4700nM)inactive (78.53%)
TAO2inactive (10001nM)inactive (85.23%)
TAO3active (1700nM)inactive (95.88%)
TNIKinactive (10001nM)-
YSK1inactive (10001nM)inactive (97.53%)
STE - STE7

Bioactivity
KinaseDRxRBC
MAP2K1inactive (10001nM)inactive (106.42%)
MAP2K2inactive (10001nM)inactive (93.21%)
MAP2K3inactive (10001nM)-
MAP2K4inactive (10001nM)-
MAP2K5active (190nM)-
MAP2K6inactive (10001nM)inactive (96.31%)
MAP2K7inactive (10001nM)-
STE - STE-Unique

Bioactivity
KinaseDRxRBC
COT-inactive (95.15%)
NIK-inactive (113.44%)

CMGC


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
208-
54-
444
322
1089
141410
222
32-
333
CMGC - CDK

Bioactivity
KinaseDRxRBC
PITSLREinactive (10001nM)-
CHEDinactive (10001nM)-
CDK11inactive (10001nM)-
PCTAIRE1inactive (10001nM)-
PCTAIRE2inactive (10001nM)-
PCTAIRE3inactive (10001nM)-
PFTAIRE2inactive (10001nM)-
PFTAIRE1inactive (10001nM)-
CMGC - CDKL

Bioactivity
KinaseDRxRBC
CDKL1inactive (10001nM)-
CDKL2inactive (10001nM)-
CDKL3inactive (10001nM)-
CDKL5inactive (10001nM)-
CMGC - CLK

Bioactivity
KinaseDRxRBC
CLK1active (2100nM)inactive (73.84%)
CLK2inactive (10001nM)inactive (91.41%)
CLK3inactive (10001nM)inactive (110.61%)
CLK4inactive (7100nM)active (45.5%)
CMGC - CK2

Bioactivity
KinaseDRxRBC
CK2a1inactive (10001nM)inactive (117.2%)
CK2a2inactive (10001nM)inactive (105.86%)
CMGC - DYRK

Bioactivity
KinaseDRxRBC
DYRK1Ainactive (10001nM)inactive (101.71%)
DYRK1Binactive (10001nM)inactive (92.76%)
DYRK2inactive (10001nM)inactive (100.71%)
HIPK1inactive (10001nM)inactive (97.73%)
HIPK2inactive (10001nM)inactive (92.1%)
HIPK3inactive (10001nM)inactive (99.8%)
HIPK4inactive (10001nM)inactive (105.48%)
PRP4inactive (10001nM)-
DYRK3-inactive (91.43%)
DYRK4-inactive (101.37%)
CMGC - MAPK

Bioactivity
KinaseDRxRBC
Erk1inactive (10001nM)inactive (104.86%)
Erk2inactive (10001nM)inactive (100.1%)
Erk3inactive (10001nM)-
Erk4inactive (10001nM)-
Erk5inactive (10001nM)-
Erk7inactive (10001nM)-
JNK1active (450nM)inactive (92.1%)
JNK2inactive (5800nM)inactive (95.9%)
JNK3active (2000nM)inactive (117.36%)
NLKinactive (10001nM)inactive (105.34%)
p38aactive (460nM)active (23.25%)
p38bactive (36nM)active (15.28%)
p38dinactive (10001nM)inactive (90.74%)
p38ginactive (10001nM)inactive (96.86%)
CMGC - GSK

Bioactivity
KinaseDRxRBC
GSK3Ainactive (10001nM)inactive (99.44%)
GSK3Binactive (10001nM)inactive (93.71%)
CMGC - RCK

Bioactivity
KinaseDRxRBC
ICKinactive (10001nM)-
MAKinactive (10001nM)-
CMGC - SRPK

Bioactivity
KinaseDRxRBC
SRPK1inactive (10001nM)inactive (98.08%)
SRPK2inactive (10001nM)inactive (102.43%)
MSSK1inactive (10001nM)inactive (100.78%)

CK1


Test Member No. in Family
Familyno. Member on 518kinaseDRxRBC
776
311
CK1 - CK1

Bioactivity
KinaseDRxRBC
CK1ainactive (10001nM)inactive (100.92%)
CK1a2inactive (10001nM)-
CK1dinactive (10001nM)inactive (89.3%)
CK1einactive (10001nM)inactive (100.96%)
CK1g1inactive (10001nM)inactive (103.92%)
CK1g2inactive (10001nM)inactive (97.31%)
CK1g3inactive (10001nM)inactive (100.95%)
CK1 - VRK

Bioactivity
KinaseDRxRBC
VRK2inactive (10001nM)-
VRK1-inactive (100.63%)