Compound in Profiling

Compound Information

Test on : RBC, Metz, Millipore

Compound Name
RBC, Metz, Millipore : 154447-36-6

Inchikey
Same : CZQHHVNHHHRRDU-N
RBC, Metz, Millipore : CZQHHVNHHHRRDU-UHFFFAOYSA-N

ChemSpider
RBC, Metz, Millipore : 3835

Pubchem CID
RBC, Metz, Millipore : 3973

ChEMBL
RBC, Metz, Millipore : CHEMBL98350

	DRx	RBC	Metz	Millipore	GPCR
bioactivity	Kd (nM)	Remain Activity (%)	Ki (nM)	Remain Activity (%)	Inhibition (%)
active criteria	<3000nM	<50%	<1000nM	<50%	>50%

AGC

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
PDK1	1	1	1	1
Akt	3	3	3	3
DMPK	7	5	3	5
GRK	7	6	1	3
RSK	8	8	4	7
PKA	5	3	2	2
PKC	9	9	5	8
PKG	2	3	2	-
PKN	3	2	1	1
SGK	3	3	1	3
NDR	4	1	-	-

AGC - PDK1

Bioactivity
Kinase	RBC	Metz	Millipore
PDK1	inactive (103.58%)	-	inactive (107%)

AGC - Akt

Bioactivity
Kinase	RBC	Metz	Millipore
AKT1	inactive (95.74%)	-	inactive (103%)
AKT2	inactive (94.01%)	-	inactive (132%)
AKT3	inactive (102.32%)	-	inactive (96%)

AGC - DMPK

Bioactivity
Kinase	RBC	Metz	Millipore
DMPK1	inactive (99.37%)	-	inactive (134%)
MRCKa	inactive (104.45%)	-	inactive (85%)
MRCKb	inactive (88.45%)	-	inactive (94%)
ROCK1	inactive (103.71%)	-	inactive (113%)
ROCK2	inactive (95.21%)	-	inactive (100%)

AGC - GRK

Bioactivity
Kinase	RBC	Metz	Millipore
BARK1	inactive (106.39%)	-	-
BARK2	inactive (99.77%)	-	-
GPRK4	inactive (96.49%)	-	-
GPRK5	inactive (91.56%)	-	inactive (97%)
GPRK6	inactive (93.02%)	-	inactive (92%)
GPRK7	inactive (112.46%)	-	inactive (96%)

AGC - RSK

Bioactivity
Kinase	RBC	Metz	Millipore
MSK1	inactive (99.48%)	-	inactive (129%)
MSK2	inactive (111.33%)	-	inactive (91%)
p70S6K	inactive (101.24%)	-	inactive (99%)
p70S6Kb	inactive (94.94%)	-	-
RSK2	inactive (98.09%)	-	inactive (69%)
RSK4	inactive (102.42%)	-	inactive (102%)
RSK1	inactive (97.35%)	-	inactive (99%)
RSK3	inactive (92.4%)	-	inactive (138%)

AGC - PKA

Bioactivity
Kinase	RBC	Metz	Millipore
PKACg	-	-	-
PRKX	inactive (100.51%)	-	inactive (119%)
PKACa	inactive (98.27%)	-	inactive (82%)

AGC - PKC

Bioactivity
Kinase	RBC	Metz	Millipore
PKCa	inactive (97.46%)	-	inactive (105%)
PKCd	inactive (95.99%)	-	inactive (114%)
PKCe	inactive (101.99%)	-	inactive (92%)
PKCh	inactive (99.05%)	-	inactive (104%)
PKCg	inactive (94.22%)	-	inactive (114%)
PKCi	inactive (99.48%)	-	inactive (92%)
PKCt	inactive (112.28%)	-	inactive (97%)
PKCz	inactive (104.71%)	-	inactive (100%)
PKCb	inactive (103.7%)	-	-

AGC - PKG

Bioactivity
Kinase	RBC	Metz	Millipore
PKG2	inactive (105.33%)	-	-
PKG1	inactive (105.18%)	-	-

AGC - PKN

Bioactivity
Kinase	RBC	Metz	Millipore
PKN1	inactive (108.79%)	-	-
PKN2	inactive (98.61%)	-	inactive (96%)

AGC - SGK

Bioactivity
Kinase	RBC	Metz	Millipore
SGK1	inactive (101.29%)	-	inactive (75%)
SGK2	inactive (97.05%)	-	inactive (87%)
SGK3	inactive (109.06%)	-	inactive (96%)

AGC - NDR

Bioactivity
Kinase	RBC	Metz	Millipore
NDR1	inactive (103.43%)	-	-

TK

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
Abl	2	2	1	2
Ack	2	1	1	1
ALK	2	2	2	1
Axl	3	3	2	3
Src	11	11	9	10
Tec	5	5	3	4
PDGFR	5	5	5	5
Csk	2	2	1	1
DDR	2	1	-	1
EGFR	4	3	3	2
Eph	14	12	1	11
FAK	2	2	2	2
Fer	2	2	2	2
FGFR	4	4	2	4
VEGFR	3	3	3	3
InsR	3	3	2	3
JakA	4	4	3	2
Musk	1	1	-	1
Ret	1	1	1	1
Met	2	2	2	2
Sev	1	1	1	1
Syk	2	2	1	2
Tie	2	1	-	1
Trk	3	3	3	2

TK - Abl

Bioactivity
Kinase	RBC	Metz	Millipore
ABL1	inactive (99.18%)	-	inactive (90%)
ABL2	inactive (98.15%)	-	inactive (108%)

TK - Ack

Bioactivity
Kinase	RBC	Metz	Millipore
ACK	inactive (88.67%)	-	inactive (76%)

TK - ALK

Bioactivity
Kinase	RBC	Metz	Millipore
ALK	inactive (92.35%)	-	inactive (73%)
LTK	inactive (87.8%)	-	-

TK - Axl

Bioactivity
Kinase	RBC	Metz	Millipore
AXL	inactive (110.29%)	-	inactive (80%)
MER	inactive (95.17%)	-	inactive (103%)
TYRO3	inactive (106.92%)	-	inactive (93%)

TK - Src

Bioactivity
Kinase	RBC	Metz	Millipore
BLK	inactive (120.35%)	-	inactive (102%)
BRK	inactive (96%)	-	inactive (101%)
SRC	inactive (96.32%)	-	inactive (93%)
FGR	inactive (97.55%)	-	inactive (115%)
FRK	inactive (101.09%)	-	inactive (97%)
FYN	inactive (100.3%)	-	inactive (88%)
HCK	inactive (98.26%)	-	inactive (66%)
LCK	inactive (104.69%)	-	inactive (109%)
SRM	inactive (103.33%)	-	-
YES	inactive (101.02%)	-	inactive (103%)
LYN	inactive (94.55%)	-	inactive (95%)

TK - Tec

Bioactivity
Kinase	RBC	Metz	Millipore
BMX	inactive (96.95%)	-	inactive (83%)
BTK	inactive (94.46%)	-	inactive (110%)
ITK	inactive (93.35%)	-	inactive (100%)
TEC	inactive (107.39%)	-	-
TXK	inactive (93.6%)	-	inactive (82%)

TK - PDGFR

Bioactivity
Kinase	RBC	Metz	Millipore
KIT	inactive (92.89%)	-	inactive (103%)
FLT3	inactive (95.63%)	-	inactive (85%)
FMS	inactive (98.27%)	-	inactive (66%)
PDGFRb	inactive (101.55%)	-	inactive (90%)
PDGFRa	inactive (94.65%)	-	inactive (109%)

TK - Csk

Bioactivity
Kinase	RBC	Metz	Millipore
CSK	inactive (88.11%)	-	inactive (107%)
CTK	inactive (84.61%)	-	-

TK - DDR

Bioactivity
Kinase	RBC	Metz	Millipore
DDR2	inactive (91.35%)	-	inactive (105%)

TK - EGFR

Bioactivity
Kinase	RBC	Metz	Millipore
EGFR	inactive (91.63%)	-	inactive (108%)
ErbB2	inactive (104.31%)	-	-
ErbB4	inactive (101.63%)	-	inactive (79%)

TK - Eph

Bioactivity
Kinase	RBC	Metz	Millipore
EphA1	inactive (101.38%)	-	inactive (86%)
EphA2	inactive (103.69%)	-	inactive (106%)
EphA3	inactive (98.74%)	-	inactive (99%)
EphA4	inactive (99.21%)	-	inactive (107%)
EphA5	inactive (113.11%)	-	inactive (104%)
EphA6	inactive (86.97%)	-	-
EphA7	inactive (101.62%)	-	inactive (91%)
EphA8	inactive (103.21%)	-	inactive (100%)
EphB1	inactive (95.86%)	-	inactive (107%)
EphB2	inactive (99.84%)	-	inactive (106%)
EphB3	inactive (94.58%)	-	inactive (108%)
EphB4	inactive (99.46%)	-	inactive (92%)

TK - FAK

Bioactivity
Kinase	RBC	Metz	Millipore
FAK	inactive (103.38%)	-	inactive (117%)
PYK2	inactive (107.01%)	-	inactive (127%)

TK - Fer

Bioactivity
Kinase	RBC	Metz	Millipore
FER	inactive (99.91%)	-	inactive (101%)
FES	inactive (96.6%)	-	inactive (111%)

TK - FGFR

Bioactivity
Kinase	RBC	Metz	Millipore
FGFR1	inactive (96.57%)	-	inactive (107%)
FGFR2	inactive (95.83%)	-	inactive (107%)
FGFR3	inactive (95.85%)	-	inactive (101%)
FGFR4	inactive (103.59%)	-	inactive (103%)

TK - VEGFR

Bioactivity
Kinase	RBC	Metz	Millipore
FLT1	inactive (85.41%)	-	inactive (89%)
FLT4	inactive (96.4%)	-	inactive (85%)
KDR	inactive (87.23%)	-	inactive (96%)

TK - InsR

Bioactivity
Kinase	RBC	Metz	Millipore
IGF1R	inactive (102.41%)	-	inactive (133%)
IRR	inactive (97.73%)	-	inactive (114%)
INSR	inactive (104.31%)	-	inactive (107%)

TK - JakA

Bioactivity
Kinase	RBC	Metz	Millipore
JAK1	inactive (108.3%)	-	-
JAK2	inactive (95.15%)	-	inactive (105%)
JAK3	inactive (102.86%)	-	inactive (92%)
TYK2	inactive (103.47%)	-	-

TK - Musk

Bioactivity
Kinase	RBC	Metz	Millipore
MUSK	inactive (101.71%)	-	inactive (88%)

TK - Ret

Bioactivity
Kinase	RBC	Metz	Millipore
RET	inactive (99.25%)	-	inactive (92%)

TK - Met

Bioactivity
Kinase	RBC	Metz	Millipore
RON	inactive (108.98%)	-	inactive (64%)
MET	inactive (127.18%)	-	inactive (109%)

TK - Sev

Bioactivity
Kinase	RBC	Metz	Millipore
ROS	inactive (98.44%)	-	inactive (93%)

TK - Syk

Bioactivity
Kinase	RBC	Metz	Millipore
SYK	inactive (99.75%)	-	inactive (114%)
ZAP70	inactive (101.58%)	-	inactive (100%)

TK - Tie

Bioactivity
Kinase	RBC	Metz	Millipore
TIE2	inactive (89.17%)	-	inactive (71%)

TK - Trk

Bioactivity
Kinase	RBC	Metz	Millipore
TRKA	inactive (95%)	-	inactive (79%)
TRKB	inactive (112.37%)	-	inactive (109%)
TRKC	inactive (95.89%)	-	-

TKL

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
STKR	12	5	1	2
RAF	5	3	1	1
IRAK	4	2	2	2
LISK	4	1	1	1
LRRK	2	1	1	-
MLK	10	5	2	2
RIPK	5	1	-	1

TKL - STKR

Bioactivity
Kinase	RBC	Metz	Millipore
ALK1	inactive (91.87%)	-	-
ALK2	inactive (91.21%)	-	-
ALK4	inactive (100.88%)	-	inactive (124%)
TGFbR1	inactive (97.54%)	-	inactive (83%)
TGFbR2	inactive (141.57%)	-	-

TKL - RAF

Bioactivity
Kinase	RBC	Metz	Millipore
ARAF	inactive (105.46%)	-	-
BRAF	inactive (95.88%)	-	-
RAF1	inactive (82.31%)	-	inactive (68%)

TKL - IRAK

Bioactivity
Kinase	RBC	Metz	Millipore
IRAK1	inactive (103.82%)	-	inactive (82%)
IRAK4	inactive (95.96%)	-	inactive (89%)

TKL - LISK

Bioactivity
Kinase	RBC	Metz	Millipore
LIMK1	inactive (98.58%)	-	inactive (101%)

TKL - LRRK

Bioactivity
Kinase	RBC	Metz	Millipore
LRRK2	inactive (96.88%)	-	-

TKL - MLK

Bioactivity
Kinase	RBC	Metz	Millipore
MLK1	inactive (108.09%)	-	inactive (88%)
MLK2	inactive (90.12%)	-	-
MLK3	inactive (101.08%)	-	-
TAK1	inactive (85.39%)	-	inactive (88%)
ZAK	inactive (94.2%)	-	-

TKL - RIPK

Bioactivity
Kinase	RBC	Metz	Millipore
RIPK2	inactive (89.87%)	-	inactive (95%)

CAMK

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CAMKL	20	13	9	12
CAMK1	5	5	2	3
CAMK2	4	4	4	3
RAD53	1	1	1	1
DAPK	5	4	2	4
DCAMKL	3	1	1	1
MAPKAPK	5	5	4	4
MLCK	5	2	-	1
PHK	2	2	1	1
PIM	3	3	3	3
PKD	3	3	2	2
TSSK	5	2	2	2
STK33	1	-	1	-

CAMK - CAMKL

Bioactivity
Kinase	RBC	Metz	Millipore
NuaK1	inactive (92.48%)	-	inactive (97%)
BRSK1	inactive (102.5%)	-	inactive (81%)
BRSK2	inactive (96.18%)	-	inactive (97%)
CHK1	inactive (104.28%)	-	inactive (84%)
LKB1	inactive (100.63%)	-	inactive (100%)
MARK1	inactive (100.36%)	-	inactive (83%)
MARK3	inactive (95.4%)	-	-
MARK4	inactive (91.43%)	-	-
MELK	inactive (91.33%)	-	inactive (91%)
PASK	inactive (90.19%)	-	inactive (125%)
QIK	inactive (96.82%)	-	-
NuaK2	inactive (95.12%)	-	-
MARK2	inactive (79.18%)	-	inactive (97%)
AMPKa1	-	-	inactive (84%)
AMPKa2	-	-	inactive (90%)
SIK	-	-	inactive (89%)

CAMK - CAMK1

Bioactivity
Kinase	RBC	Metz	Millipore
CaMK1a	inactive (96.68%)	-	inactive (104%)
CaMK1b	inactive (98.36%)	-	-
CaMK1d	active (47.9%)	-	inactive (93%)
CaMK1g	inactive (93.8%)	-	-
CaMK4	inactive (103.82%)	-	inactive (107%)

CAMK - CAMK2

Bioactivity
Kinase	RBC	Metz	Millipore
CaMK2a	inactive (91.13%)	-	-
CaMK2b	inactive (109.97%)	-	inactive (93%)
CaMK2d	inactive (100.27%)	-	inactive (102%)
CaMK2g	inactive (90.48%)	-	inactive (100%)

CAMK - RAD53

Bioactivity
Kinase	RBC	Metz	Millipore
CHK2	inactive (93.72%)	-	inactive (88%)

CAMK - DAPK

Bioactivity
Kinase	RBC	Metz	Millipore
DAPK1	inactive (90.08%)	-	inactive (82%)
DAPK2	inactive (125.67%)	-	inactive (92%)
DRAK1	inactive (93.55%)	-	inactive (103%)
DAPK3	inactive (96.47%)	-	inactive (94%)

CAMK - DCAMKL

Bioactivity
Kinase	RBC	Metz	Millipore
DCLK2	inactive (97.6%)	-	inactive (91%)
DCLK1	-	-	-

CAMK - MAPKAPK

Bioactivity
Kinase	RBC	Metz	Millipore
MAPKAPK2	inactive (102.52%)	-	inactive (85%)
MAPKAPK3	inactive (101.28%)	-	inactive (88%)
MAPKAPK5	inactive (94.09%)	-	inactive (89%)
MNK1	inactive (102.86%)	-	-
MNK2	inactive (103.34%)	-	inactive (105%)

CAMK - MLCK

Bioactivity
Kinase	RBC	Metz	Millipore
smMLCK	inactive (97.77%)	-	inactive (76%)
skMLCK	inactive (102.25%)	-	-

CAMK - PHK

Bioactivity
Kinase	RBC	Metz	Millipore
PHKg1	inactive (90.13%)	-	-
PHKg2	inactive (97.22%)	-	inactive (97%)

CAMK - PIM

Bioactivity
Kinase	RBC	Metz	Millipore
PIM1	inactive (66.82%)	-	active (47%)
PIM2	inactive (105.74%)	-	inactive (88%)
PIM3	inactive (88.54%)	-	inactive (87%)

CAMK - PKD

Bioactivity
Kinase	RBC	Metz	Millipore
PKD1	inactive (98.33%)	-	inactive (110%)
PKD3	inactive (92.47%)	-	-
PKD2	inactive (93.77%)	-	inactive (101%)

CAMK - TSSK

Bioactivity
Kinase	RBC	Metz	Millipore
TSSK1	inactive (101.2%)	-	inactive (97%)
TSSK2	inactive (91.39%)	-	inactive (83%)

CAMK - STK33

Bioactivity
Kinase	RBC	Metz	Millipore
STK33	inactive (92.12%)	-	inactive (99%)

STE

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
STE11	8	3	-	1
STE-Unique	2	2	-	-
STE20	31	23	9	14
STE7	7	3	2	3

STE - STE11

Bioactivity
Kinase	RBC	Metz	Millipore
MAP3K5	inactive (96.24%)	-	inactive (98%)
MAP3K2	inactive (100.61%)	-	-
MAP3K3	inactive (93.38%)	-	-

STE - STE-Unique

Bioactivity
Kinase	RBC	Metz	Millipore
COT	inactive (98.24%)	-	-
NIK	inactive (100.67%)	-	-

STE - STE20

Bioactivity
Kinase	RBC	Metz	Millipore
GCK	inactive (87.77%)	-	inactive (82%)
HGK	inactive (93.51%)	-	-
KHS1	inactive (92.15%)	-	-
LOK	inactive (97.13%)	-	inactive (89%)
MINK	inactive (94.55%)	-	inactive (87%)
MST1	inactive (87.81%)	-	inactive (87%)
MST2	-	-	inactive (103%)
MST3	inactive (97.07%)	-	inactive (59%)
MST4	inactive (97.18%)	-	-
OSR1	inactive (118.17%)	-	-
PAK1	inactive (97.81%)	-	-
PAK2	inactive (102.65%)	-	inactive (90%)
PAK3	inactive (104.28%)	-	inactive (64%)
PAK4	inactive (92.75%)	-	inactive (97%)
PAK5	inactive (103.74%)	-	inactive (89%)
PAK6	inactive (114.86%)	-	inactive (96%)
SLK	inactive (101.87%)	-	-
YSK1	inactive (115.77%)	-	-
STLK3	inactive (78.45%)	-	-
TAO1	inactive (86.43%)	-	inactive (96%)
TAO2	inactive (108.77%)	-	inactive (109%)
TAO3	inactive (88.19%)	-	inactive (93%)
MYO3B	inactive (103.75%)	-	-

STE - STE7

Bioactivity
Kinase	RBC	Metz	Millipore
MAP2K1	inactive (88.81%)	-	inactive (103%)
MAP2K2	inactive (96.79%)	-	-
MAP2K6	inactive (97.51%)	-	inactive (72%)
MAP2K7	-	-	inactive (91%)

Other

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
Aur	3	3	2	3
CAMKK	2	2	1	-
Haspin	1	1	-	1
IKK	4	4	4	3
NEK	11	8	2	5
TOPK	1	1	1	-
PLK	4	3	3	3
SgK496	1	1	-	-
NAK	4	1	-	-
TTK	1	1	-	-
ULK	5	3	-	2
WEE	3	1	1	-
WNK	4	2	-	2
TLK	2	1	-	1
CDC7	1	-	1	-

Other - Aur

Bioactivity
Kinase	RBC	Metz	Millipore
AurA	inactive (98.96%)	-	inactive (78%)
AurB	inactive (99.62%)	-	inactive (89%)
AurC	inactive (97.03%)	-	inactive (101%)

Other - CAMKK

Bioactivity
Kinase	RBC	Metz	Millipore
CaMKK1	inactive (105.2%)	-	-
CaMKK2	inactive (83.26%)	-	-

Other - Haspin

Bioactivity
Kinase	RBC	Metz	Millipore
Haspin	inactive (93.45%)	-	inactive (98%)

Other - IKK

Bioactivity
Kinase	RBC	Metz	Millipore
IKKa	inactive (103.99%)	-	inactive (109%)
IKKb	inactive (100.19%)	-	inactive (105%)
IKKe	inactive (100.08%)	-	-
TBK1	inactive (94.08%)	-	inactive (68%)

Other - NEK

Bioactivity
Kinase	RBC	Metz	Millipore
NEK1	inactive (86.71%)	-	-
NEK11	inactive (101.62%)	-	inactive (99%)
NEK2	inactive (89.82%)	-	inactive (81%)
NEK4	inactive (95.07%)	-	-
NEK6	inactive (111.95%)	-	inactive (94%)
NEK7	inactive (92.13%)	-	inactive (98%)
NEK9	inactive (100.96%)	-	-
NEK3	inactive (102.19%)	-	inactive (104%)

Other - TOPK

Bioactivity
Kinase	RBC	Metz	Millipore
PBK	inactive (110.18%)	-	-

Other - PLK

Bioactivity
Kinase	RBC	Metz	Millipore
PLK1	inactive (67.12%)	-	inactive (61%)
PLK2	inactive (98.92%)	-	inactive (104%)
PLK3	inactive (71.94%)	-	inactive (88%)
PLK4	-	-	-

Other - SgK496

Bioactivity
Kinase	RBC	Metz	Millipore
SgK496	inactive (112.52%)	-	-

Other - NAK

Bioactivity
Kinase	RBC	Metz	Millipore
MPSK1	inactive (97.48%)	-	-

Other - TTK

Bioactivity
Kinase	RBC	Metz	Millipore
TTK	inactive (102.96%)	-	-

Other - ULK

Bioactivity
Kinase	RBC	Metz	Millipore
ULK1	inactive (101.62%)	-	-
ULK2	inactive (112.63%)	-	inactive (101%)
ULK3	inactive (103.48%)	-	inactive (100%)

Other - WEE

Bioactivity
Kinase	RBC	Metz	Millipore
Wee1	inactive (76.45%)	-	-

Other - WNK

Bioactivity
Kinase	RBC	Metz	Millipore
Wnk2	inactive (109.71%)	-	inactive (107%)
Wnk3	inactive (89.21%)	-	inactive (103%)

Other - TLK

Bioactivity
Kinase	RBC	Metz	Millipore
TLK2	inactive (83.2%)	-	inactive (98%)

Other - CDC7

Bioactivity
Kinase	RBC	Metz	Millipore
CDC7	-	-	-

CK1

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CK1	7	6	5	4
VRK	3	1	-	1

CK1 - CK1

Bioactivity
Kinase	RBC	Metz	Millipore
CK1d	inactive (100.25%)	-	inactive (85%)
CK1g1	inactive (103.71%)	-	inactive (90%)
CK1g2	inactive (94.42%)	-	inactive (81%)
CK1g3	inactive (92.39%)	-	inactive (90%)
CK1a	active (0%)	-	-
CK1e	inactive (103.19%)	-	-

CK1 - VRK

Bioactivity
Kinase	RBC	Metz	Millipore
VRK1	inactive (85.41%)	-	-
VRK2	-	-	inactive (104%)

CMGC

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
CK2	3	2	1	2
CLK	4	4	2	2
DYRK	10	9	6	4
MAPK	14	10	8	10
GSK	2	2	2	2
SRPK	3	3	1	3
CDK	20	-	7	-

CMGC - CK2

Bioactivity
Kinase	RBC	Metz	Millipore
CK2a1	inactive (64.84%)	-	inactive (54%)
CK2a2	inactive (93.91%)	-	inactive (104%)

CMGC - CLK

Bioactivity
Kinase	RBC	Metz	Millipore
CLK1	inactive (112.13%)	-	-
CLK2	inactive (100.4%)	-	inactive (111%)
CLK3	inactive (107.42%)	-	inactive (80%)
CLK4	inactive (89.1%)	-	-

CMGC - DYRK

Bioactivity
Kinase	RBC	Metz	Millipore
DYRK1A	inactive (97.31%)	-	-
DYRK1B	inactive (96.82%)	-	-
DYRK2	inactive (90.83%)	-	inactive (93%)
DYRK3	inactive (100.36%)	-	-
DYRK4	inactive (91.93%)	-	-
HIPK1	inactive (110.96%)	-	inactive (94%)
HIPK2	inactive (122.4%)	-	inactive (90%)
HIPK3	inactive (119.98%)	-	inactive (85%)
HIPK4	inactive (101.86%)	-	-

CMGC - MAPK

Bioactivity
Kinase	RBC	Metz	Millipore
Erk1	inactive (103.96%)	-	inactive (78%)
Erk2	inactive (70.28%)	-	inactive (102%)
JNK3	inactive (87.08%)	-	inactive (70%)
NLK	inactive (99.84%)	-	inactive (92%)
p38a	inactive (87.65%)	-	inactive (90%)
p38b	inactive (96.19%)	-	inactive (94%)
p38d	inactive (93.34%)	-	inactive (101%)
p38g	inactive (104.13%)	-	inactive (97%)
JNK1	inactive (106.28%)	-	inactive (97%)
JNK2	inactive (101.59%)	-	inactive (103%)

CMGC - GSK

Bioactivity
Kinase	RBC	Metz	Millipore
GSK3A	inactive (93.54%)	-	inactive (103%)
GSK3B	inactive (96.92%)	-	inactive (89%)

CMGC - SRPK

Bioactivity
Kinase	RBC	Metz	Millipore
MSSK1	inactive (95.49%)	-	inactive (109%)
SRPK1	inactive (104.31%)	-	inactive (105%)
SRPK2	inactive (98.16%)	-	inactive (95%)

CMGC - CDK

Bioactivity
Kinase	RBC	Metz	Millipore
CDC2	-	-	-
CDK2	-	-	-
CDK5	-	-	-
CDK8	-	inactive (3162.28nM)	-
CDK7	-	-	-
CDK9	-	-	-
CDK11	-	inactive (>100000nM)	-

Atypical

Test Member No. in Family
Family	no. Member on 518kinase	RBC	Metz	Millipore
PDHK	5	1	-	-
Alpha	6	-	1	1
PIKK	6	-	-	1

Atypical - PDHK

Bioactivity
Kinase	RBC	Metz	Millipore
PDHK1	inactive (103.58%)	-	-

Atypical - Alpha

Bioactivity
Kinase	RBC	Metz	Millipore
eEF2K	-	-	inactive (88%)

Atypical - PIKK

Bioactivity
Kinase	RBC	Metz	Millipore
FRAP	-	-	active (24%)