Q9UKE5 TNIK

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Group: STE
Family: STE20
PDB Structure Num: 3
FDA approved drugs from DrugBank: Fostamatinib

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structure	FDA kinase drug	inchikey	kinase profiling data count	kinase profiling label	ChEMBL data count	ChEMBL label	vote label
		BPNUQXPIQBZCMR-LJQANCHMSA-N	1	active	-	-	active
		WJEOLQLKVOPQFV-UHFFFAOYSA-N	1	inactive	-	-	inactive
		MPVGZUGXCQEXTM-UHFFFAOYSA-N	1	active	-	-	active
		CVWXJKQAOSCOAB-UHFFFAOYSA-N	1	active	-	-	active
		RITAVMQDGBJQJZ-UHFFFAOYSA-N	1	active	-	-	active
		RAHBGWKEPAQNFF-UHFFFAOYSA-N	1	inactive	-	-	inactive
		ODPGGGTTYSGTGO-UHFFFAOYSA-N	1	active	-	-	active
		OVPNQJVDAFNBDN-UHFFFAOYSA-N	1	inactive	-	-	inactive
		QYZOGCMHVIGURT-UHFFFAOYSA-N	1	inactive	-	-	inactive
		XXJWYDDUDKYVKI-UHFFFAOYSA-N	1	active	-	-	active
		CYOHGALHFOKKQC-UHFFFAOYSA-N	1	inactive	-	-	inactive
		XQVVPGYIWAGRNI-QFIPXVFZSA-N	1	inactive	-	-	inactive
-		FCLPVPNWFDOVKL-DQSJHHFOSA-N	1	active	-	-	active
		ULXXDDBFHOBEHA-INIZCTEOSA-N	1	inactive	-	-	inactive
		MVCOAUNKQVWQHZ-UHFFFAOYSA-N	1	active	-	-	active
		PSPFQEBFYXJZEV-UHFFFAOYSA-N	1	inactive	-	-	inactive
		OUSFTKFNBAZUKL-UHFFFAOYSA-N	1	inactive	-	-	inactive
		WCWUXEGQKLTGDX-NSHDSACASA-N	1	active	-	-	active
		UIARLYUEJFELEN-FMLDBKJISA-N	1	active	-	-	active
-		KCOYQXZDFIIGCY-CZIZESTLSA-N	1	active	-	-	active
		YABJJWZLRMPFSI-UHFFFAOYSA-N	1	active	-	-	active
		OMZCMEYTWSXEPZ-UHFFFAOYSA-N	1	inactive	-	-	inactive
		GFMMXOIFOQCCGU-UHFFFAOYSA-N	1	inactive	-	-	inactive
		UJLAWZDWDVHWOW-DGCLKSJQSA-N	1	inactive	-	-	inactive
	Crizotinib	KTEIFNKAUNYNJU-GFCCVEGCSA-N	1	inactive	-	-	inactive
	Dasatinib	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	1	active	-	-	active
	Erlotinib	AAKJLRGGTJKAMG-UHFFFAOYSA-N	1	inactive	-	-	inactive
		CXQHYVUVSFXTMY-UHFFFAOYSA-N	1	active	-	-	active
		BIIVYFLTOXDAOV-YVEFUNNKSA-N	1	inactive	-	-	inactive
		DEZZLWQELQORIU-UHFFFAOYSA-N	1	active	-	-	active
		LHNIIDJUOCFXAP-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Gefitinib	XGALLCVXEZPNRQ-UHFFFAOYSA-N	1	inactive	-	-	inactive
-		XWFUWIOJOVXAMS-FXIRQEPWSA-N	1	inactive	-	-	inactive
		ZHJGWYRLJUCMRT-QGZVFWFLSA-N	1	inactive	-	-	inactive
		KGPGFQWBCSZGEL-ZDUSSCGKSA-N	1	inactive	-	-	inactive
		MYQAUKPBNJWPIE-UHFFFAOYSA-N	1	inactive	-	-	inactive
		JWNPDZNEKVCWMY-UHFFFAOYSA-N	1	active	-	-	active
	Imatinib	KTUFNOKKBVMGRW-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Ruxolitinib	HFNKQEVNSGCOJV-OAHLLOKOSA-N	1	inactive	-	-	inactive
-		OLESUNNHPSUJLS-UHFFFAOYSA-N	1	active	-	-	active
		SHPFDGWALWEPGS-UHFFFAOYSA-N	1	active	-	-	active
		YYLKKYCXAOBSRM-UHFFFAOYSA-N	1	active	-	-	active
	Lapatinib	BCFGMOOMADDAQU-UHFFFAOYSA-N	1	inactive	-	-	inactive
		UUADYKVKJIMIPA-UHFFFAOYSA-N	1	inactive	-	-	inactive
		ZCBUQCWBWNUWSU-SFHVURJKSA-N	1	inactive	-	-	inactive
		ZNOLRTPMNMPLHY-UHFFFAOYSA-N	1	inactive	-	-	inactive
		UXXQOJXBIDBUAC-UHFFFAOYSA-N	1	inactive	-	-	inactive
		HHFBDROWDBDFBR-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Nilotinib	HHZIURLSWUIHRB-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Pazopanib	CUIHSIWYWATEQL-UHFFFAOYSA-N	1	active	-	-	active
		VAARYSWULJUGST-UHFFFAOYSA-N	1	active	-	-	active
		OYONTEXKYJZFHA-OAQYLSRUSA-N	1	active	-	-	active
		TUVCWJQQGGETHL-UHFFFAOYSA-N	1	inactive	-	-	inactive
		BMGQWWVMWDBQGC-PZFYLCKJSA-N	1	active	-	-	active
		YZDJQTHVDDOVHR-UHFFFAOYSA-N	1	active	-	-	active
-		MTICIDWIKCANDD-UHFFFAOYSA-N	1	active	-	-	active
		YCOYDOIWSSHVCK-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Tamatinib	NHHQJBCNYHBUSI-UHFFFAOYSA-N	1	active	-	-	active
		JRNJNYBQQYBCLE-UHFFFAOYSA-N	1	inactive	-	-	inactive
		CDMGBJANTYXAIV-HHHXNRCGSA-N	1	active	-	-	active
		BCZUAADEACICHN-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Bosutinib	UBPYILGKFZZVDX-UHFFFAOYSA-N	1	active	-	-	active
	Sorafenib	MLDQJTXFUGDVEO-UHFFFAOYSA-N	1	inactive	-	-	inactive
		HKSZLNNOFSGOKW-FYTWVXJKSA-N	1	active	-	-	active
		CTNPALGJUAXMMC-PMFHANACSA-N	1	active	-	-	active
	Sunitinib	WINHZLLDWRZWRT-ATVHPVEESA-N	1	active	-	-	active
		QQWUGDVOUVUTOY-UHFFFAOYSA-N	1	active	-	-	active
		UJIAQDJKSXQLIT-UHFFFAOYSA-N	1	inactive	-	-	inactive
		JOOXLOJCABQBSG-UHFFFAOYSA-N	1	inactive	-	-	inactive
	Vandetanib	UHTHHESEBZOYNR-UHFFFAOYSA-N	1	active	-	-	active
		GCIKSSRWRFVXBI-UHFFFAOYSA-N	1	active	-	-	active
		VEPKQEUBKLEPRA-UHFFFAOYSA-N	1	inactive	-	-	inactive
		ZLZJYPLAARWUEF-UHFFFAOYSA-N	-	-	2	active	active
		YTRKGSFSZXFLJT-UHFFFAOYSA-N	-	-	2	exclude	exclude
		OEJWLFFGGRLKTR-UHFFFAOYSA-N	-	-	2	exclude	exclude
		FOWKPAQNTXMWQQ-UHFFFAOYSA-N	-	-	2	exclude	exclude
		JKDVQSBZXOTCNO-UHFFFAOYSA-N	-	-	2	exclude	exclude
		KXMSGPHFWCUEMO-UHFFFAOYSA-N	-	-	2	exclude	exclude
		BXCCJKYWJVBVGD-UHFFFAOYSA-N	-	-	1	active	active
		QABZWIZUOWNALE-UHFFFAOYSA-N	-	-	2	exclude	exclude
		GOMSKBLQVUFHHS-UHFFFAOYSA-N	-	-	1	active	active
		WYFRHLVGTKZBGO-UHFFFAOYSA-N	-	-	1	active	active
		GGIBPOCMZCLEEG-UHFFFAOYSA-N	-	-	1	active	active
		RFZDGPIOKDAECB-UHFFFAOYSA-N	-	-	1	active	active
		YHMCLJVLKPGWEY-UHFFFAOYSA-N	-	-	1	active	active
		AGPQQUHGXGMBGH-UHFFFAOYSA-N	-	-	1	active	active
		ITQOLEAFQJRNAT-UHFFFAOYSA-N	-	-	1	active	active
		KHPCIHZXOGHCLY-UHFFFAOYSA-N	-	-	1	active	active
		VHKZQKMURKDWFP-CMDGGOBGSA-N	-	-	1	inactive	inactive
		SCOCKGQONUJONV-LLVKDONJSA-N	-	-	1	inactive	inactive
		LXVJPLXSANONIL-UHFFFAOYSA-N	-	-	1	active	active
		YEKOQLAMWYTEEQ-UHFFFAOYSA-N	-	-	1	inactive	inactive
		BDIJIDPPFZISFQ-JLHYYAGUSA-N	-	-	1	inactive	inactive
		QHZBBYLAKDGXAM-UHFFFAOYSA-N	-	-	4	exclude	exclude
		PIQCTGMSNWUMAF-UHFFFAOYSA-N	-	-	3	active	active
		NIPBOAVGKUKGLT-UHFFFAOYSA-N	-	-	1	inactive	inactive
		ZEHBZHZMQSHZFI-UHFFFAOYSA-N	-	-	1	inactive	inactive