Q13164 Erk5
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Group: CMGC
Family: MAPK
PDB Structure Num: 7
FDA approved drugs from DrugBank: Fostamatinib
| structure | FDA kinase drug | inchikey | kinase profiling data count | kinase profiling label | ChEMBL data count | ChEMBL label | vote label |
|---|---|---|---|---|---|---|---|
 | BPNUQXPIQBZCMR-LJQANCHMSA-N | 1 | inactive | - | - | inactive | |
 | WJEOLQLKVOPQFV-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | MPVGZUGXCQEXTM-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | CVWXJKQAOSCOAB-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | RITAVMQDGBJQJZ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | RAHBGWKEPAQNFF-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | ODPGGGTTYSGTGO-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OVPNQJVDAFNBDN-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | QYZOGCMHVIGURT-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | XXJWYDDUDKYVKI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | CYOHGALHFOKKQC-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | XQVVPGYIWAGRNI-QFIPXVFZSA-N | 1 | inactive | - | - | inactive | |
| - | FCLPVPNWFDOVKL-DQSJHHFOSA-N | 1 | active | - | - | active | |
 | ULXXDDBFHOBEHA-INIZCTEOSA-N | 1 | inactive | - | - | inactive | |
 | MVCOAUNKQVWQHZ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | PSPFQEBFYXJZEV-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | OUSFTKFNBAZUKL-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | WCWUXEGQKLTGDX-NSHDSACASA-N | 1 | inactive | - | - | inactive | |
 | UIARLYUEJFELEN-FMLDBKJISA-N | 1 | active | - | - | active | |
| - | KCOYQXZDFIIGCY-CZIZESTLSA-N | 1 | inactive | - | - | inactive | |
 | YABJJWZLRMPFSI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OMZCMEYTWSXEPZ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | GFMMXOIFOQCCGU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | UJLAWZDWDVHWOW-DGCLKSJQSA-N | 1 | inactive | - | - | inactive | |
 | Crizotinib | KTEIFNKAUNYNJU-GFCCVEGCSA-N | 1 | active | - | - | active |
 | Dasatinib | ZBNZXTGUTAYRHI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Erlotinib | AAKJLRGGTJKAMG-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | CXQHYVUVSFXTMY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | BIIVYFLTOXDAOV-YVEFUNNKSA-N | 1 | active | - | - | active | |
 | DEZZLWQELQORIU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | LHNIIDJUOCFXAP-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Gefitinib | XGALLCVXEZPNRQ-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
| - | XWFUWIOJOVXAMS-FXIRQEPWSA-N | 1 | inactive | - | - | inactive | |
 | ZHJGWYRLJUCMRT-QGZVFWFLSA-N | 1 | inactive | - | - | inactive | |
 | KGPGFQWBCSZGEL-ZDUSSCGKSA-N | 1 | inactive | - | - | inactive | |
 | MYQAUKPBNJWPIE-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | JWNPDZNEKVCWMY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Imatinib | KTUFNOKKBVMGRW-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Ruxolitinib | HFNKQEVNSGCOJV-OAHLLOKOSA-N | 1 | inactive | - | - | inactive |
| - | OLESUNNHPSUJLS-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | SHPFDGWALWEPGS-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | YYLKKYCXAOBSRM-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | Lapatinib | BCFGMOOMADDAQU-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | UUADYKVKJIMIPA-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | ZCBUQCWBWNUWSU-SFHVURJKSA-N | 1 | inactive | - | - | inactive | |
 | ZNOLRTPMNMPLHY-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | UXXQOJXBIDBUAC-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | HHFBDROWDBDFBR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Nilotinib | HHZIURLSWUIHRB-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | Pazopanib | CUIHSIWYWATEQL-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | VAARYSWULJUGST-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | OYONTEXKYJZFHA-OAQYLSRUSA-N | 1 | active | - | - | active | |
 | TUVCWJQQGGETHL-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | BMGQWWVMWDBQGC-PZFYLCKJSA-N | 1 | inactive | - | - | inactive | |
 | YZDJQTHVDDOVHR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
| - | MTICIDWIKCANDD-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | YCOYDOIWSSHVCK-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Tamatinib | NHHQJBCNYHBUSI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | JRNJNYBQQYBCLE-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | CDMGBJANTYXAIV-HHHXNRCGSA-N | 1 | inactive | - | - | inactive | |
 | BCZUAADEACICHN-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | Bosutinib | UBPYILGKFZZVDX-UHFFFAOYSA-N | 1 | active | - | - | active |
 | Sorafenib | MLDQJTXFUGDVEO-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | HKSZLNNOFSGOKW-FYTWVXJKSA-N | 1 | active | - | - | active | |
 | CTNPALGJUAXMMC-PMFHANACSA-N | 1 | inactive | - | - | inactive | |
 | Sunitinib | WINHZLLDWRZWRT-ATVHPVEESA-N | 1 | inactive | - | - | inactive |
 | QQWUGDVOUVUTOY-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | UJIAQDJKSXQLIT-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | JOOXLOJCABQBSG-UHFFFAOYSA-N | 1 | active | - | - | active | |
 | Vandetanib | UHTHHESEBZOYNR-UHFFFAOYSA-N | 1 | inactive | - | - | inactive |
 | GCIKSSRWRFVXBI-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | VEPKQEUBKLEPRA-UHFFFAOYSA-N | 1 | inactive | - | - | inactive | |
 | DDTPGANIPBKTNU-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | YSFFGUHMDPYPAW-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | WUWXJIFZTHONGM-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | HGHFBVBNHYJNHK-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | VVPYTOVXFOGRIN-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | BFRFMGINYAWFLS-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | DDFSQXFBHZHGHD-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | QAPAJIZPZGWAND-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | CRFHZXHUGPCWJA-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | QRVNXVTYIYXPER-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | PVPMWNDEOMUSJK-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | GIYVCQVJJYRKEE-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | JGVXSQJYBQAPAE-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | YYTFTZONXCQXLW-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | NFNBVXVXMQZSGB-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | NYHLZQOMTUZDHV-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | VOMMOJXYDRSJDB-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | VHGSQSKYNALGRI-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | RHSOYHKODVPGTH-UHFFFAOYSA-N | - | - | 1 | inactive | inactive | |
 | BQNHHYZMVCQLJG-VHXPQNKSSA-N | - | - | 1 | inactive | inactive | |
 | HOMJAAIVTDVQJA-IZHYLOQSSA-N | - | - | 1 | active | active | |
 | QCLXNOBXQUWUEW-UHFFFAOYSA-N | - | - | 1 | active | active | |
 | NEQZWEXWOFPKOT-JADIVCKYSA-N | - | - | 1 | inactive | inactive | |
 | ZEHBZHZMQSHZFI-UHFFFAOYSA-N | - | - | 1 | inactive | inactive |